caa a22 4500 477045324 CHVBK 20180405111328.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/BF01895101 doi (NATIONALLICENCE)springer-10.1007/BF01895101 Age-associated changes in detrusor sensory function in women with lower urinary tract symptoms [Elektronische Daten] [D. Collas, J. Malone-Lee] This study examined changes in bladder sensation which occur with age in women. 1381 women (age range 20-95 years, mean 54.9) with symptoms of lower urinary tract dysfunction underwent urodynamic study. The bladder capacity at which they first became aware of the desire to void was taken as a quantitative measure of bladder sensation. Maximum bladder capacity fell in the eighth and ninth decades (H=95.84, df=7,P=0.00), but by contrast bladder capacity at first desire to void rose progressively in association with age, both in the group as a whole (H=17.13, df=7,P=0.017) and in a subgroup with detrusor instability (n=952, H=15.42, df=7,P=0.032). This rise in capacity points to a decrease in bladder sensation in association with age. This is not due to neurological disease, antimuscarinic drugs or oestrogens, as the median capacity at first desire to void of these three subgroups did not differ significantly from that of the group as a whole. The International Urogynecology Journal, 1996 Aging nationallicence Bladder nationallicence Detrusor instability nationallicence Sensation nationallicence Urodynamics nationallicence Collas D. Division of Geriatrics, Department of Medicine, University College London Medical School, St. Pancras Hospital, 4 St Pancras Way, NW1 0PE, London, UK aut Malone-Lee J. Division of Geriatrics, Department of Medicine, University College London Medical School, St. Pancras Hospital, 4 St Pancras Way, NW1 0PE, London, UK aut International Urogynecology Journal Springer-Verlag 7/1(1996-01-01), 24-29 0937-3462 7:1<24 1996 7 192 https://doi.org/10.1007/BF01895101 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01895101 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Collas D. Division of Geriatrics, Department of Medicine, University College London Medical School, St. Pancras Hospital, 4 St Pancras Way, NW1 0PE, London, UK aut NATIONALLICENCE 700 1- Malone-Lee J. Division of Geriatrics, Department of Medicine, University College London Medical School, St. Pancras Hospital, 4 St Pancras Way, NW1 0PE, London, UK aut NATIONALLICENCE 773 0- International Urogynecology Journal Springer-Verlag 7/1(1996-01-01), 24-29 0937-3462 7:1<24 1996 7 192 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 397137621 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer