caa a22 4500 47704557X CHVBK 20180405111329.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/BF01907071 doi (NATIONALLICENCE)springer-10.1007/BF01907071 Clarke B. Department of Obstetrics and Gynecology, University of Queensland and Royal Women's Hospital, Herston Q 4029, Queensland, Australia aut Anticholinergic medication for the unstable bladder: Prospective trials of imipramine/propantheline versus penthienate and oxybutynin versus penthienate [Elektronische Daten] [B. Clarke] A comparison was made of three drug regimens: imipramine (Tofranil)/propantheline, oxybutynin (Ditropan) and penthienate bromide (Monodral). Two comparative trials were performed in prospective studies, using a randomization and cross-over design. All the drugs were found to improve the urinary symptoms and urodynamic changes associated with the unstable bladder, but penthienate was shown to be more effective than imipramine/propantheline. Its effect on the unstable bladder was equivalent to that of oxybutynin. Side-effects were common and most common with oxybutynin. However, the inability of these drugs to prevent the uninhibited detrusor contractions of the unstable bladder consistently and objectively was demonstrated. The International Urogynecology Journal, 1996 Anticholinergics nationallicence Imipramine nationallicence Oxybutynin nationallicence Penthienate nationallicence Propantheline nationallicence Randomized trial nationallicence Unstable bladder nationallicence International Urogynecology Journal Springer-Verlag 7/4(1996-07-01), 191-195 0937-3462 7:4<191 1996 7 192 https://doi.org/10.1007/BF01907071 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01907071 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Clarke B. Department of Obstetrics and Gynecology, University of Queensland and Royal Women's Hospital, Herston Q 4029, Queensland, Australia aut NATIONALLICENCE 773 0- International Urogynecology Journal Springer-Verlag 7/4(1996-07-01), 191-195 0937-3462 7:4<191 1996 7 192 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer