caa a22 4500 477055990 CHVBK 20180405111346.0 cr unu---uuuuu 170330e19961201xx s 000 0 eng 10.1007/s002280050185 doi (NATIONALLICENCE)springer-10.1007/s002280050185 Evaluation of personality as a component of the healthy condition of volunteers participating in phase I studies [Elektronische Daten] [D. Berto, S. Milleri, L. Squassante, P. A. Baroldi] Objective The present study was conceived in order to recommend use of the Minnesota Multiphasic Personality Inventory for the evaluation of the personality of volunteers participating in Phase I clinical trials. The study was intended to describe personality profiles as objectively as possible, attempting to identify any common traits or tendencies, and to evaluate whether age or cultural background can be associated with significant differences in volunteer personality profiles. Subjects: 358 subjects were evaluated (290 males and 68 females; mean age 30 y, range 18-78 y). Mean values of scales and indices were compared and analysed, both for the sample as a whole and on the basis of its breakdown according to sex, age and education. Results: No psychopathological values were found in terms of sex and education. The mean profile showed common traits of a substantially balanced, self-assured, reliable person, motivated by extremely realistic objectives. Conclusions: The Minnesota Multiphasic Personality Inventory seems to be a useful tool for screening healthy volunteers. Springer-Verlag Berlin Heidelberg, 1996 Key words Phase I clinical trials nationallicence Minnesota Multiphasic Personality Inventory nationallicence volunteers nationallicence psychological assessment nationallicence Berto D. Clinical Psychology Adviser, Padua, Italy, IT aut Milleri S. Clinical Pharmacology, Glaxo Wellcome SpA Medicines Research Centre, Via Fleming, 4, I-37135 Verona, Italy, IT aut Squassante L. Clinical Pharmacology, Glaxo Wellcome SpA Medicines Research Centre, Via Fleming, 4, I-37135 Verona, Italy, IT aut Baroldi P. A. Clinical Pharmacology, Glaxo Wellcome SpA Medicines Research Centre, Via Fleming, 4, I-37135 Verona, Italy, IT aut https://doi.org/10.1007/s002280050185 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002280050185 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Berto D. Clinical Psychology Adviser, Padua, Italy, IT aut NATIONALLICENCE 700 1- Milleri S. Clinical Pharmacology, Glaxo Wellcome SpA Medicines Research Centre, Via Fleming, 4, I-37135 Verona, Italy, IT aut NATIONALLICENCE 700 1- Squassante L. Clinical Pharmacology, Glaxo Wellcome SpA Medicines Research Centre, Via Fleming, 4, I-37135 Verona, Italy, IT aut NATIONALLICENCE 700 1- Baroldi P. A. Clinical Pharmacology, Glaxo Wellcome SpA Medicines Research Centre, Via Fleming, 4, I-37135 Verona, Italy, IT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer