caa a22 4500 477056776 CHVBK 20180405111348.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/s002280050175 doi (NATIONALLICENCE)springer-10.1007/s002280050175 Diminished effect of etidronate in vitamin D deficient osteopenic postmenopausal women [Elektronische Daten] [J. C. Koster, W. H. L. Hackeng, H. Mulder] Objective: The effects of vitamin D deficiency in osteopenic postmenopausal women treated with intermittent cyclical etidronate have been studied. Bone mass and biochemical parameters as bone markers were measured before and after one year of therapy with intermittent cyclical etidronate. Results: In 30 patients without vitamin D deficiency, bone mass in the lumbal spine and femoral neck was significantly increased compared to 28 vitamin D deficient patients. After cyclical intermittent etidronate therapy, serum osteocalcin and PTH were significantly increased in the vitamin D deficient patients, whereas in non-vitamin D deficient patients they did not change. Conclusion: It is worthwhile measuring serum vitamin D before starting etidronate therapy and, in case of deficiency, to give vitamin D. Springer-Verlag Berlin Heidelberg, 1996 Key words Etidronate nationallicence Vitamin D deficiency nationallicence postmenopausal women nationallicence osteoporosis nationallicence Koster J. C. Medisch Onderzoekcentrum Good Clinical Practice, Groot Hertoginnelaan 34, NL-2517 EH Den Haag, The Netherlands, NL aut Hackeng W. H. L. Praktijk voor laboratoriumdiagnostiek, Burg. Van de Minnelaan 3, NL-3211 AE Geervliet, The Netherlands, NL aut Mulder H. Medisch Onderzoekcentrum Good Clinical Practice, Walenburgerweg 33, NL-3039 AC Roterdam, The Netherlands, NL aut https://doi.org/10.1007/s002280050175 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002280050175 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koster J. C. Medisch Onderzoekcentrum Good Clinical Practice, Groot Hertoginnelaan 34, NL-2517 EH Den Haag, The Netherlands, NL aut NATIONALLICENCE 700 1- Hackeng W. H. L. Praktijk voor laboratoriumdiagnostiek, Burg. Van de Minnelaan 3, NL-3211 AE Geervliet, The Netherlands, NL aut NATIONALLICENCE 700 1- Mulder H. Medisch Onderzoekcentrum Good Clinical Practice, Walenburgerweg 33, NL-3039 AC Roterdam, The Netherlands, NL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer