caa a22 4500 477057071 CHVBK 20180405111349.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/s002280050099 doi (NATIONALLICENCE)springer-10.1007/s002280050099 Effect of physical activity on serum concentrations of digoxin and digitoxin [Elektronische Daten] [W. Grille, U. Welter, K. Johnsen, K. D. Kolenda, H. Löffler] Objective: To study the influence of moderate physical activity on serum concentrations of digoxin, digitoxin and albumin. Methods: Blood samples were drawn from 10 consecutive mobile patients on digoxin and 12 patients on digitoxin therapy before and following a 10-min walking period. Digitalis serum concentrations were determined by radioimmunoassay, and albumin serum concentrations by laser nephelometry. Results: Following physical activity, digoxin serum concentrations dropped immediately to 79% of baseline values and remained significantly decreased for 20 min. Digitoxin concentrations did not change significantly. Conclusion: In contrast to digoxin, the effect of physical activity the serum concentration of digitoxin can be disregarded. Springer-Verlag Berlin Heidelberg, 1996 Key words Digoxin nationallicence Digitoxin nationallicence albumin nationallicence serum concentration nationallicence physical activity nationallicence Grille W. First Medical Department, Community Hospital Kiel, Chemnitzstrasse 33, D-24116 Kiel, Germany, DE aut Welter U. Department of Anesthesiology, University Hospital Kiel, Kiel, Germany, DE aut Johnsen K. Ostsee-Klinik, Schönberg i.H., Germany, DE aut Kolenda K. D. Ostsee-Klinik, Schönberg i.H., Germany, DE aut Löffler H. Second Medical Department, University Hospital Kiel, Kiel, Germany, DE aut https://doi.org/10.1007/s002280050099 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002280050099 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Grille W. First Medical Department, Community Hospital Kiel, Chemnitzstrasse 33, D-24116 Kiel, Germany, DE aut NATIONALLICENCE 700 1- Welter U. Department of Anesthesiology, University Hospital Kiel, Kiel, Germany, DE aut NATIONALLICENCE 700 1- Johnsen K. Ostsee-Klinik, Schönberg i.H., Germany, DE aut NATIONALLICENCE 700 1- Kolenda K. D. Ostsee-Klinik, Schönberg i.H., Germany, DE aut NATIONALLICENCE 700 1- Löffler H. Second Medical Department, University Hospital Kiel, Kiel, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer