caa a22 4500 477061524 CHVBK 20180405111402.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF01061910 doi (NATIONALLICENCE)springer-10.1007/BF01061910 Recognition and management of the hypercoagulable states: A decade of change [Elektronische Daten] [Scott Goodnight, Thomas DeLoughery, Richard Press] Hereditary and acquired thrombophilias are common causes of venous thromboembolism. Widely, available laboratory assays demonstrate that up to 25% of patients with a first deep venous thrombosis and as many as 60% of patients with recurrent venous thrombosis have one or more coagulation defects. Three important thrombotic disorders have been described in the last decade: hereditary resistance to activated protein C, homocyst(e)inemia, and antiphospholipid antibodies. Identification of patients with these abnormalities will help determine the duration and intensity of anticoagulant therapy, facilitate detection of affected family members, and allow effective antithrombotic prophylaxis during such high-risk situations as surgery, childbirth, or trauma. Finally, in some instances, specific treatment is available for managing these conditions. Kluwer Academic Publishers, 1996 hypercoagulable state nationallicence APC resistance nationallicence activated protein C nationallicence homocyst(e)inemia nationallicence antiphospholipid antibodies nationallicence Goodnight Scott Division of Laboratory Medicine L-471, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201-3098, Portland, OR aut DeLoughery Thomas Division of Laboratory Medicine L-471, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201-3098, Portland, OR aut Press Richard Division of Laboratory Medicine L-471, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201-3098, Portland, OR aut Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 2/4(1996-03-01), 271-274 0929-5305 2:4<271 1996 2 11239 https://doi.org/10.1007/BF01061910 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01061910 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Goodnight Scott Division of Laboratory Medicine L-471, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201-3098, Portland, OR aut NATIONALLICENCE 700 1- DeLoughery Thomas Division of Laboratory Medicine L-471, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201-3098, Portland, OR aut NATIONALLICENCE 700 1- Press Richard Division of Laboratory Medicine L-471, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201-3098, Portland, OR aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 2/4(1996-03-01), 271-274 0929-5305 2:4<271 1996 2 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer