caa a22 4500 477061532 CHVBK 20180405111402.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF01061909 doi (NATIONALLICENCE)springer-10.1007/BF01061909 Management of anticoagulant therapy: The dutch experience [Elektronische Daten] [Frits Rosendaal, Felix van der Meer, Suzanne Cannegieter] In the Netherlands, outpatient oral anticoagulant therapy is monitored by a system of specialized anticoagulation clinics whose purpose is to make anticoagulant therapy as safe and effective as possible. In this paper we present the daily routine in one of these anticoagulation clinics (the Leiden clinic), which serves a catchment area with about 500,000 inhabitants. Several levels of quality control can be distinguished in the anticoagulation clinic. One level is the evaluation and standardization of laboratory methods, which includes participation in multicentered quality assurance programs. A second level is therapeutic quality control, which is the evaluation of how well a clinic maintains the patients within the specified target range of anticoagulant intensity. A third level is clinical quality control, which includes clinical outcome research. Outcome research includes studies into complications associated with treatment (e.g., bleeds), risk factors of treatment, and the optimal intensity of anticoagulant treatment. Kluwer Academic Publishers, 1996 anticoagulant nationallicence quality control nationallicence management nationallicence Rosendaal Frits Anticoagulation Clinic Leiden, The Netherlands aut van der Meer Felix Anticoagulation Clinic Leiden, The Netherlands aut Cannegieter Suzanne Anticoagulation Clinic Leiden, The Netherlands aut Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 2/4(1996-03-01), 265-269 0929-5305 2:4<265 1996 2 11239 https://doi.org/10.1007/BF01061909 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01061909 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rosendaal Frits Anticoagulation Clinic Leiden, The Netherlands aut NATIONALLICENCE 700 1- van der Meer Felix Anticoagulation Clinic Leiden, The Netherlands aut NATIONALLICENCE 700 1- Cannegieter Suzanne Anticoagulation Clinic Leiden, The Netherlands aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 2/4(1996-03-01), 265-269 0929-5305 2:4<265 1996 2 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer