caa a22 4500 47706177X CHVBK 20180405111402.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00226403 doi (NATIONALLICENCE)springer-10.1007/BF00226403 A noninvasive approach for the treatment of patients with suspected pulmonary embolism [Elektronische Daten] [Russell Hull, Graham Pineo, Gary Raskob] The diagnosis of pulmonary embolism is challenging because the signs and symptoms are nonspecific, the findings on ventilation-perfusion lung scans are often nondiagnostic, and pulmonary angiography, although definitive, is not always available. We previously reported that serial non-invasive leg testing provided a practical, noninvasive alternative to pulmonary angiography in patients who had nondiagnostic lung scans and adequate cardiorespiratory reserve. In this prospective cohort study of 1564 patients with suspected pulmonary embolism, ventilation-perfusion lung scanning and serial impedance plethysmography were used to objectively assess prognosis. Only 12 of 627 patients (1.9%) with nondiagnostic lung scans but normal serial leg testing results who were not given anticoagulants had venous thromboembolism during long-term follow-up. Noninvasive serial leg testing can avoid the need for pulmonary angiography for the majority of patients, identify those with proximal vein thrombosis who require anticoagulant treatment, and avert treatment and further investigation of patients who have adequate cardiorespiratory reserve. Kluwer Academic Publishers, 1996 pulmonary embolism nationallicence pulmonary angiography nationallicence ventilation/perfusion lung scan nationallicence impedance plethysmography nationallicence anticoagulants nationallicence Hull Russell Division of General Internal Medicine, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada aut Pineo Graham Division of General Internal Medicine, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada aut Raskob Gary Department of Biostatistics and Epidemiology, Department of Medicine, University of Oklahoma, Oklahoma City, Oklahoma, USA aut Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 3/1(1996-03-01), 5-8 0929-5305 3:1<5 1996 3 11239 https://doi.org/10.1007/BF00226403 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00226403 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hull Russell Division of General Internal Medicine, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada aut NATIONALLICENCE 700 1- Pineo Graham Division of General Internal Medicine, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada aut NATIONALLICENCE 700 1- Raskob Gary Department of Biostatistics and Epidemiology, Department of Medicine, University of Oklahoma, Oklahoma City, Oklahoma, USA aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 3/1(1996-03-01), 5-8 0929-5305 3:1<5 1996 3 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer