caa a22 4500 477061893 CHVBK 20180405111403.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF00181658 doi (NATIONALLICENCE)springer-10.1007/BF00181658 Anticoagulation in congestive cardiomyopathy: Steps toward defining the great unknown [Elektronische Daten] [Fred Spencer, Richard Becker] It is generally agreed that congestive cardiomyopathy predisposes to the formation of cardiac thrombus and in turn systemic thromboembolism. Several uncontrolled studies have confirmed this association and have prompted wide-scale recommendations for long-term anticoagulation in these patients. Clinical studies have also attempted to identify patients at high risk for embolic events. The presence of cardiac thrombus, its topographic characteristics, the severity of left ventricular dysfunction, and decreased apical flow velocities may each represent markers of increased risk. Driven by the lack of definitive data addressing this issue, several pleas from the medical community have come forth for a large, randomized controlled trial of anticoagulation in congestive cardiomyopathy. Accordingly, a multicenter trial comparing aspirin, warfarin, or placebo as prophylaxis against thromboembolism has been proposed and if conducted will provide valuable information regarding the management of patients with congestive cardiomyopathy. Kluwer Academic Publishers, 1996 cardiomyopathy nationallicence thromboembolism nationallicence anticoagulation nationallicence Spencer Fred Cardiovascular Thrombosis Research Center, University of Massachusetts Medical School, Worcester, Massachusetts aut Becker Richard Cardiovascular Thrombosis Research Center, University of Massachusetts Medical School, Worcester, Massachusetts aut Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 3/3(1996-09-01), 171-179 0929-5305 3:3<171 1996 3 11239 https://doi.org/10.1007/BF00181658 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00181658 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Spencer Fred Cardiovascular Thrombosis Research Center, University of Massachusetts Medical School, Worcester, Massachusetts aut NATIONALLICENCE 700 1- Becker Richard Cardiovascular Thrombosis Research Center, University of Massachusetts Medical School, Worcester, Massachusetts aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 3/3(1996-09-01), 171-179 0929-5305 3:3<171 1996 3 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer