caa a22 4500 477062113 CHVBK 20180405111403.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF00132406 doi (NATIONALLICENCE)springer-10.1007/BF00132406 Theroux Pierre Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada aut Enhancing thrombolysis with adjunctive therapy [Elektronische Daten] [Pierre Theroux] The striking clinical benefits that can be derived from thrombolytic therapy in acute myocardial infarction emphasize the need for further improvement of our reperfusion strategies. New approaches in that direction include the development of more efficient thrombolytic drugs as well as an adjunctive therapy to control the ongoing thrombogenic stimulation. Aspirin is already useful in this regard as well as heparin with recombinant tissue-type plasminogen activator. The field of antithrombotic therapy is rapidly expanding with the development of potent drugs targeted at inhibiting specific steps of platelet activation and of the coagulation cascade. This new therapy provides opportunities to better understand the pathophysiological processes involved in acute ischemic syndromes and to modulate them. This article reviews the adjunctive antithrombotic therapy currently available or under clinical investigation with the potential of enhancing the benefits of thrombolysis. Kluwer Academic Publishers, 1996 antiplatelets nationallicence anticoagulants nationallicence thrombolytic agents nationallicence adjunctive therapy nationallicence Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 3/2(1996-06-01), 135-143 0929-5305 3:2<135 1996 3 11239 https://doi.org/10.1007/BF00132406 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00132406 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Theroux Pierre Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 3/2(1996-06-01), 135-143 0929-5305 3:2<135 1996 3 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer