caa a22 4500 477067301 CHVBK 20180405111416.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/BF02458387 doi (NATIONALLICENCE)springer-10.1007/BF02458387 Determination of pulmonary mean transit time and cardiac output using a one-dimensional model [Elektronische Daten] [C. Le Sech, A. Capderou] In this work, we show that a one-dimensional model of the blood flow across the lungs can reproduce the evolution of a bolus versus the time. Solving the differential equation governing the bolus concentration in the framework of this model, we determine the solution which fulfills Gaussian initial boundary conditions. An effective parameter related to the ratio of a diffusion coefficient to the square of the mean speed of the flow is defined. The determination of its numerical values following a semi-empirical approach enables us to know accurately the mean transit time and the cardiac output. The results have been compared to other methods, and were found in good agreement. Such an approach could be of interest in all studies where the knowledge of flow—including micro-circulation—is needed. Society for Mathematical Biology, 1996 Le Sech C. Laboratoire des Collisions Atomiques et Moléculaires (Unité de Recherches Associée au CNRS N0 281), Université de Paris-Sud, Bât. 351, 91405, Orsay Cedex, France aut Capderou A. Laboratoire de Physiologie (Unité de Recherches Associée au CNRS N0 1159), Centre Chirurgical Marie Lannelongue, 133 Ave de la Résistance, 92350, Le Plessis Robinson, France aut Bulletin of Mathematical Biology Kluwer Academic Publishers 58/6(1996-11-01), 1155-1170 0092-8240 58:6<1155 1996 58 11538 https://doi.org/10.1007/BF02458387 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02458387 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Le Sech C. Laboratoire des Collisions Atomiques et Moléculaires (Unité de Recherches Associée au CNRS N0 281), Université de Paris-Sud, Bât. 351, 91405, Orsay Cedex, France aut NATIONALLICENCE 700 1- Capderou A. Laboratoire de Physiologie (Unité de Recherches Associée au CNRS N0 1159), Centre Chirurgical Marie Lannelongue, 133 Ave de la Résistance, 92350, Le Plessis Robinson, France aut NATIONALLICENCE 773 0- Bulletin of Mathematical Biology Kluwer Academic Publishers 58/6(1996-11-01), 1155-1170 0092-8240 58:6<1155 1996 58 11538 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer