caa a22 4500 477067352 CHVBK 20180405111416.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/BF02460591 doi (NATIONALLICENCE)springer-10.1007/BF02460591 Panetta John Department of Mathematics and Statistics, Old Dominion University, 23529, Norfolk, VA, USA aut A mathematical model of periodically pulsed chemotherapy: Tumor recurrence and metastasis in a competitive environment [Elektronische Daten] [John Panetta] A competition model describing tumor-normal cell interaction with the added effects of periodically pulsed chemotherapy is discussed. The model describes parameter conditions needed to prevent relapse following attempts to remove the tumor or tumor metastasis. The effects of resistant tumor subpopulations are also investigated and recurrence prevention strategies are explored. Society for Mathematical Biology, 1996 Bulletin of Mathematical Biology Kluwer Academic Publishers 58/3(1996-05-01), 425-447 0092-8240 58:3<425 1996 58 11538 https://doi.org/10.1007/BF02460591 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02460591 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Panetta John Department of Mathematics and Statistics, Old Dominion University, 23529, Norfolk, VA, USA aut NATIONALLICENCE 773 0- Bulletin of Mathematical Biology Kluwer Academic Publishers 58/3(1996-05-01), 425-447 0092-8240 58:3<425 1996 58 11538 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer