caa a22 4500 47706860X CHVBK 20180405111419.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/BF02905712 doi (NATIONALLICENCE)springer-10.1007/BF02905712 A to Z: Vitamin A and zinc, the miracle duo [Elektronische Daten] [Edgar Molina, Janak Patel] Dietary micronutrients such as vitamins and trace minerals are known modulators of host immune responses against common pathogens. In this respect, vitamin A and zinc have recently received increased attention. Severalin vivo andin vitro studies suggest that vitamin A may be a critical player in the mucosal immune responses in the respiratory and gastrointestinal tracts, particularly in undernourished children. The effect may be mediated primarily by stabilization of the membrane of mucosal epithelial cells, as well as enhanced leukocyte functions. The beneficial effect of vitamin A therapy in reducing measles-associated morbidity and mortality suggests its crucial role in defenses against viral pathogens. Zinc is also known affect leukocyte functions such as phagocytosis and T-lymphocyte-mediated immune responses. However, unlike vitamin A, zinc has been investigated primarily for its effects on bacterial infections. Dietary supplementation or therapeutic treatment with vitamin A and zinc may be a cheap yet effective means of preventing or treating infections in highly susceptible populations. Additional studies, however, are required to better define the types of pathogens and the specific human populations that may benefit from such therapy. Dr. K C Chaudhuri Foundation, 1996 Vitamin A nationallicence Zinc nationallicence Immunity nationallicence Nutrition nationallicence Molina Edgar Division of Pediatric Infectious Diseases, Children's Hospital, Medical Branch, University of Texas, 301 University Boulevard Rm. 3.320, 77555-0371, Galveston, Texas, USA aut Patel Janak Division of Pediatric Infectious Diseases, Children's Hospital, Medical Branch, University of Texas, 301 University Boulevard Rm. 3.320, 77555-0371, Galveston, Texas, USA aut The Indian Journal of Pediatrics Springer India 63/4(1996-07-01), 427-431 0019-5456 63:4<427 1996 63 12098 https://doi.org/10.1007/BF02905712 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02905712 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Molina Edgar Division of Pediatric Infectious Diseases, Children's Hospital, Medical Branch, University of Texas, 301 University Boulevard Rm. 3.320, 77555-0371, Galveston, Texas, USA aut NATIONALLICENCE 700 1- Patel Janak Division of Pediatric Infectious Diseases, Children's Hospital, Medical Branch, University of Texas, 301 University Boulevard Rm. 3.320, 77555-0371, Galveston, Texas, USA aut NATIONALLICENCE 773 0- The Indian Journal of Pediatrics Springer India 63/4(1996-07-01), 427-431 0019-5456 63:4<427 1996 63 12098 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer