caa a22 4500 477068731 CHVBK 20180405111419.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/BF02905723 doi (NATIONALLICENCE)springer-10.1007/BF02905723 Systemic lupus erythematosus [Elektronische Daten] [Marisa Klein-Gitelman, Michael Miller] Systemic Lupus Erythematosus (SLE) of childhood is a complex and challenging disease which can occur at any age. Identification of disease early in it's course and aggressive, appropriate management leads to improved outcome for an individual child. The history of SLE indicates how much progress has been made in the last quarter century. A discussion of the etiopathogenesis of SLE demonstrates the complexity of the syndrome. This is followed by a description of clinical manifestations, including diagnostic criteria, differential diagnosis and suggested methods for eliciting important symptoms to make the diagnosis. Evaluation of specific organs is next reviewed highlighting critical organ manifestations that are significant for future prognosis. Treatment of SLE includes a variety of medications, including non-steroidal anti-inflammatory medications, steroids and immuno-suppressive drugs. Attention to physical activity, stress and nutrition is equally important. Signs and symptoms that indicate disease flare or infection are described. Lastly, related syndromes are reviewed. Dr. K C Chaudhuri Foundation, 1996 SLE nationallicence Antibodies nationallicence Medications nationallicence Related syndromes nationallicence Klein-Gitelman Marisa Division of Immunology and Rheumatology, Children's Memorial Hospital and Northwestern University Medical School, 2300 Children's Plaza, 60614, Chicago, IL, USA aut Miller Michael Division of Immunology and Rheumatology, Children's Memorial Hospital and Northwestern University Medical School, 2300 Children's Plaza, 60614, Chicago, IL, USA aut The Indian Journal of Pediatrics Springer India 63/4(1996-07-01), 485-500 0019-5456 63:4<485 1996 63 12098 https://doi.org/10.1007/BF02905723 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02905723 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Klein-Gitelman Marisa Division of Immunology and Rheumatology, Children's Memorial Hospital and Northwestern University Medical School, 2300 Children's Plaza, 60614, Chicago, IL, USA aut NATIONALLICENCE 700 1- Miller Michael Division of Immunology and Rheumatology, Children's Memorial Hospital and Northwestern University Medical School, 2300 Children's Plaza, 60614, Chicago, IL, USA aut NATIONALLICENCE 773 0- The Indian Journal of Pediatrics Springer India 63/4(1996-07-01), 485-500 0019-5456 63:4<485 1996 63 12098 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer