caa a22 4500 477069029 CHVBK 20180405111420.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF02730819 doi (NATIONALLICENCE)springer-10.1007/BF02730819 Kumar Vijay Department of Pediatrics, University of Ottawa, Canada aut Interstitial lung disease [Elektronische Daten] [Vijay Kumar] Interstitial lung disease in children is a complex group of disorders whose etiology and pathogenesis is not entirely clear. Although the basic pathogenesis has been extrapolated from adult studies, its relevance in the pediatric population can be questioned. Several classifications of this condition have been put forward but Liebow's histologic classification is well accepted. Clinical manifestations are non-specific and can vary from no symptoms and a positive chest X-ray to more characteristic signs and symptoms. The triad of tachypnea, intercostal retractions and dry crackles is characteristic. Chest roentgenograms are a useful diagnostic tool and CT scans help to stage disease severity. Spirometry classically shows a restrictive pattern. Lung biopsy is the gold standard for establishing a diagnosis. Corticosteroids are the cornerstone of treatment in this condition. Thus, in view of the multifactorial nature of this disease, more extensive multi-centre prospective studies are required in order to better understand this rather complex group of disorders. Dr. K C Chaudhuri Foundation, 1996 Interstitial lung disease nationallicence Alveolitis nationallicence Liebow's classification nationallicence Interstitial pneumonitis nationallicence Giant-cell pneumonitis nationallicence Plasma-cell interstitial pneumonitis nationallicence Lymphoid-interstitial pneumonitis, Velcro crackles nationallicence BAL fluid nationallicence The Indian Journal of Pediatrics Springer India 63/5(1996-09-01), 673-677 0019-5456 63:5<673 1996 63 12098 https://doi.org/10.1007/BF02730819 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02730819 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Kumar Vijay Department of Pediatrics, University of Ottawa, Canada aut NATIONALLICENCE 773 0- The Indian Journal of Pediatrics Springer India 63/5(1996-09-01), 673-677 0019-5456 63:5<673 1996 63 12098 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer