caa a22 4500 477069177 CHVBK 20180405111420.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF02730815 doi (NATIONALLICENCE)springer-10.1007/BF02730815 Does B.C.G. vaccination prevent or postpone the occurrence of tuberculous meningitis? [Elektronische Daten] [S. Mittal, Vyom Aggarwal, Alka Rastogi, Neel Saini] The reported efficiency of B.C.G. vaccine in prevention of primary childhood or sputum positive adult tuberculosis vary widely but it is believed to offer significant protection against hematogenous forms of tuberculosis. The present hospital-based, case control study was aimed at evaluation of impact of B.C.G. vaccination on one of the hematogenous forms of tuberculosis i.e. Tuberculous meningitis (TBM). Records of cases of TBM admitted in the pediatric wards of Lok Nayak Hospital, Delhi, over one year were analyzed retrospectively for B.C.G. positivity status and age distribution. The results were compared with similar data obtained from a control group comprising of non-TBM cases in pediatric wards of same hospital, recruited on 2 days, separated by an interval of three weeks. No statistically significant difference was found in B.C.G. positivity status of cases and control groups. However, there was an obvious trend in age distribution among cases of TBM with respect to the B.C.G. status, with a significantly higher proportion of B.C.G. vaccinated children in over 5-year age group, as compared to those in under 5 year age group. The results, therefore, indicate probable effectiveness of B.C.G. against TBM only for a limited duration i.e. single B.C.G. immunization only postpones rather than prevent the occurrence of TBM. Dr. K C Chaudhuri Foundation, 1996 B.C.G nationallicence Tuberculous meningitis nationallicence Childhood tuberculosis nationallicence Mittal S. Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut Aggarwal Vyom Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut Rastogi Alka Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut Saini Neel Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut The Indian Journal of Pediatrics Springer India 63/5(1996-09-01), 659-664 0019-5456 63:5<659 1996 63 12098 https://doi.org/10.1007/BF02730815 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02730815 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mittal S. Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut NATIONALLICENCE 700 1- Aggarwal Vyom Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut NATIONALLICENCE 700 1- Rastogi Alka Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut NATIONALLICENCE 700 1- Saini Neel Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi aut NATIONALLICENCE 773 0- The Indian Journal of Pediatrics Springer India 63/5(1996-09-01), 659-664 0019-5456 63:5<659 1996 63 12098 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer