caa a22 4500 477069819 CHVBK 20180405111422.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF01691311 doi (NATIONALLICENCE)springer-10.1007/BF01691311 Clinical diagnosis of mycobacterial diseases versus autopsy findings in 350 patients with AIDS [Elektronische Daten] [A. Monforte, L. Vago, A. Gori, S. Antinori, F. Franzetti, C. Antonacci, E. Sala, L. Catozzi, L. Testa, R. Esposito, M. Nebuloni, M. Moroni] Three-hundred fifty consecutively autopsied AIDS patients in Milan, Italy, were studied to determine the frequencies of clinical and postmortem diagnoses of mycobacterial diseases, to evaluate the clinical histories of those patients with mycobacterial diseases, and to investigate the reasons for nondiagnosis of mycobacterial diseases during life. Seventy-eight patients (22.3%) had mycobacterial diseases. In 64 cases (18.3%) the diagnosis was made antemortem and in 50 (14.2%) at autopsy; there were 36 cases of concordant clinical and postmortem diagnoses. Nontuberculous mycobacterioses (NTM) were diagnosed in 41 patients (20 clinical/postmortem diagnoses, 11 clinical diagnoses, and 10 postmortem diagnoses), extrapulmonary tuberculosis (TB) in 19 patients (7 clinical/postmortem, 8 clinical, 4 postmortem), and pulmonary TB in 18 patients (9 clinical/postmortem, 9 clinical). Patients with a clinical diagnosis of mycobacteriosis but with no pathological evidence of disease at autopsy were considered to have recovered on the basis of negative culture findings and prolonged antimycobacterial treatment. In Italian patients with AIDS, NTM occurs less frequently and TB more frequently than in American AIDS patients. At least some of the patients reported in this study seemed to have recovered from mycobacterial disease after prolonged treatment. The lack of diagnosis during life can be attributed to aspecific symptoms, a rapidly terminal course, and the presence of concomitant opportunistic diseases. MMV Medizin Verlag GmbH, 1996 Monforte A. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Vago L. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Gori A. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Antinori S. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Franzetti F. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Antonacci C. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Sala E. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Catozzi L. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Testa L. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Esposito R. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Nebuloni M. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut Moroni M. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/6(1996-06-01), 453-458 0934-9723 15:6<453 1996 15 10096 https://doi.org/10.1007/BF01691311 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691311 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Monforte A. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Vago L. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Gori A. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Antinori S. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Franzetti F. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Antonacci C. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Sala E. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Catozzi L. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Testa L. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Esposito R. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Nebuloni M. Department of Pathology, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 700 1- Moroni M. Clinic of Infectious Diseases, University of Milan, L. Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/6(1996-06-01), 453-458 0934-9723 15:6<453 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer