caa a22 4500 477069843 CHVBK 20180405111422.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF01691321 doi (NATIONALLICENCE)springer-10.1007/BF01691321 Adenosine deaminase isoenzymes in typhoid fever [Elektronische Daten] [J. Ungerer, H. Burger, S. Bissbort, W. Vermaak] The activity of serum adenosine deaminase and its isoenzymes (ADA1 and ADA2) was measured in the sera of 55 patients with clinically diagnosed typhoid fever, 46 of whom were seropositive forSalmonella typhi infection. At presentation 95% of the serologically positive patients had increased serum adenosine deaminase activity. The increase in activity was greater than that of other frequently measured enzymes. Isoenzyme ADA2 accounted for 84% of the activity, indicating a monocyte/macrophage origin. Results show that in patients with typhoid fever, serum adenosine deaminase, particularly its isoenzyme ADA2, may be regarded as a marker for monocyte/macrophage activation and could be valuable in diagnosis. MMV Medizin Verlag GmbH, 1996 Ungerer J. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut Burger H. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut Bissbort S. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut Vermaak W. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/6(1996-06-01), 510-512 0934-9723 15:6<510 1996 15 10096 https://doi.org/10.1007/BF01691321 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691321 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ungerer J. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut NATIONALLICENCE 700 1- Burger H. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut NATIONALLICENCE 700 1- Bissbort S. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut NATIONALLICENCE 700 1- Vermaak W. Department of Chemical Pathology, University of Pretoria, PO Box 2034, 0001, Pretoria, South Africa aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/6(1996-06-01), 510-512 0934-9723 15:6<510 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer