caa a22 4500 477069886 CHVBK 20180405111422.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF01691956 doi (NATIONALLICENCE)springer-10.1007/BF01691956 Prospective evaluation of fever of unknown origin in patients infected with the human immunodeficiency virus [Elektronische Daten] [F. Lozano, J. Torre-Cisneros, A. Bascuñana, J. Polo, P. Viciana, M. García-Ordóñez, J. Hernández-Quero, M. Márquez, A. Vergara, F. Díez, E. Pujo, M. Torres-Tortosa, J. Pasquau, J. Hernández-Burruezo, I. Suárez] The aim of this study was to determine the frequency and aetiology of fever of unknown origin (FUO) in patients infected with the human immunodeficiency virus (HIV), to assess the value of the tests used in its diagnosis, and to evaluate possible models of diagnosis for the causes found most frequently. One hundred twenty-eight (3.5%) of 3603 hospitalised HIV-positive patients evaluated from October 1992 to December 1993 had FUO, defined by established criteria. Eighty-six percent of patients with FUO had previously progressed to AIDS. The median CD4+ cell count was 46/mm3. A definite diagnosis was made in 96 (75%) of the 128 patients and a possible diagnosis in 24 (18.7%), whilst no diagnosis was made in eight cases (6.2%). Tuberculosis (48.3%), visceral leishmaniasis (16%), and infection byMycobacterium avium complex (6.9%) were the diseases found most frequently. The most useful diagnostic tests were liver biopsy (68.9%) and bone marrow aspirate/biopsy (39.7%). It is not possible to predict clinically the cases of FUO due to tuberculosis, whilst thrombocytopaenia < 100,000 cells/mm3 alone is useful for differentiating the cases of visceral leishmaniasis, with a negative predictive value of 95.2%. MMV Medizin Verlag GmbH, 1996 Lozano F. Infectious Diseases Section, Hospital Universitario de Valme, Autovía de Cádiz s/n, 41014, Seville, Spain aut Torre-Cisneros J. Hospital Universitario Reina Sofía, Cordoba, Spain aut Bascuñana A. Hospital Universitario Puerta del Mar, Cádiz, Spain aut Polo J. Infectious Diseases Section, Hospital Universitario de Valme, Autovía de Cádiz s/n, 41014, Seville, Spain aut Viciana P. Hospital Universitario Virgen del Rocío, Seville, Spain aut García-Ordóñez M. Hospital Regional Carlos Haya, Málaga, Spain aut Hernández-Quero J. Hospital Clinico Universitario, Granada, Spain aut Márquez M. Hospital Universitario Virgen de la Victoria, Málaga, Spain aut Vergara A. Hospital Universitario de Puerto Real, Spain aut Díez F. Hospital Torrecárdenas, Almería, Spain aut Pujo E. Hospital Juan Ramón Jiménez, Huelva, Spain aut Torres-Tortosa M. Hospital Punta de Europa, Algeciras, Spain aut Pasquau J. Hospital Virgen de las Nieves, Granada, Spain aut Hernández-Burruezo J. Hospital General, Jaén, Spain aut Suárez I. Hospital Infanta Elena, Huelva, Spain aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/9(1996-09-01), 705-711 0934-9723 15:9<705 1996 15 10096 https://doi.org/10.1007/BF01691956 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691956 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lozano F. Infectious Diseases Section, Hospital Universitario de Valme, Autovía de Cádiz s/n, 41014, Seville, Spain aut NATIONALLICENCE 700 1- Torre-Cisneros J. Hospital Universitario Reina Sofía, Cordoba, Spain aut NATIONALLICENCE 700 1- Bascuñana A. Hospital Universitario Puerta del Mar, Cádiz, Spain aut NATIONALLICENCE 700 1- Polo J. Infectious Diseases Section, Hospital Universitario de Valme, Autovía de Cádiz s/n, 41014, Seville, Spain aut NATIONALLICENCE 700 1- Viciana P. Hospital Universitario Virgen del Rocío, Seville, Spain aut NATIONALLICENCE 700 1- García-Ordóñez M. Hospital Regional Carlos Haya, Málaga, Spain aut NATIONALLICENCE 700 1- Hernández-Quero J. Hospital Clinico Universitario, Granada, Spain aut NATIONALLICENCE 700 1- Márquez M. Hospital Universitario Virgen de la Victoria, Málaga, Spain aut NATIONALLICENCE 700 1- Vergara A. Hospital Universitario de Puerto Real, Spain aut NATIONALLICENCE 700 1- Díez F. Hospital Torrecárdenas, Almería, Spain aut NATIONALLICENCE 700 1- Pujo E. Hospital Juan Ramón Jiménez, Huelva, Spain aut NATIONALLICENCE 700 1- Torres-Tortosa M. Hospital Punta de Europa, Algeciras, Spain aut NATIONALLICENCE 700 1- Pasquau J. Hospital Virgen de las Nieves, Granada, Spain aut NATIONALLICENCE 700 1- Hernández-Burruezo J. Hospital General, Jaén, Spain aut NATIONALLICENCE 700 1- Suárez I. Hospital Infanta Elena, Huelva, Spain aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/9(1996-09-01), 705-711 0934-9723 15:9<705 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer