caa a22 4500 477070221 CHVBK 20180405111423.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/BF01709368 doi (NATIONALLICENCE)springer-10.1007/BF01709368 Serologic responses to Rhodococcus equi in individuals with and without human immunodeficiency virus infection [Elektronische Daten] [V. Vullo, C. Mastroianni, M. Lichtner, F. Mengoni, E. Chiappini, C. D'Agostino, S. Delia] Thirty healthy blood donors, 15 workers from horse-breeding farms, 69 human immunodeficiency virus (HIV)-negative persons at risk for HIV infection, 125 HIV-infected subjects withoutRhodococcus equi infection, and nine HIV-infected patients withRhodococcus equi pneumonia were evaluated in order to detect serum antibodies toRhodococcus equi precipitate-soluble antigen by an enzyme immunoassay (EIA). Whereas EIA values for healthy donors, horse farm workers, individuals at risk for HIV infection, and HIV-positive subjects withoutRhodococcus equi infection were comparable, HIV-infected patients with rhodococcal disease had significantly higherRhodococcus equi antibody levels (p<0.0001). The clinical outcome ofRhodococcus equi pneumonia was more severe in subjects who had low levels of specific antibodies, whereas patients who recovered had elevatedRhodococcus equi antibody levels over time. Immunoblot studies showed that bothRhodococcus equi-infected patients and foals recognized a protein band of approximately 60 kDa in theRhodococcus equi precipitate-soluble antigen. On the other hand, theRhodococcus equi-infected patients did not react with the diffuse 15 to 17 kDa virulence-associated proteins that represent important virulence factors both in mice and horses. MMV Medizin Verlag GmbH, 1996 Vullo V. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut Mastroianni C. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut Lichtner M. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut Mengoni F. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut Chiappini E. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut D'Agostino C. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut Delia S. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/7(1996-07-01), 588-594 0934-9723 15:7<588 1996 15 10096 https://doi.org/10.1007/BF01709368 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01709368 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vullo V. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 700 1- Mastroianni C. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 700 1- Lichtner M. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 700 1- Mengoni F. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 700 1- Chiappini E. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 700 1- D'Agostino C. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 700 1- Delia S. Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/7(1996-07-01), 588-594 0934-9723 15:7<588 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer