caa a22 4500 477070442 CHVBK 20180405111423.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF01591361 doi (NATIONALLICENCE)springer-10.1007/BF01591361 van't Wout J. Department of Infectious Diseases, University Hospital Leiden, Building 1, C5P, PO Box 9600, 2300, RC Leiden, The Netherlands aut Fluconazole treatment of Candidal infections caused by non- Albicans Candida species [Elektronische Daten] [J. van't Wout] Fluconazole is an effective alternative to amphotericin B for the treatment of serious infections caused byCandida albicans. Through a literature survey of candidal infections caused by non-albicans Candida spp., 43 cases treated with fluconazole were found. The most common causative organisms wereCandida parapsilosis (14 patients),Candida glabrata (12 patients), andCandida tropicalis (11 patients). The dose of fluconazole varied from 50 to 400 mg daily. The median duration of treatment was 21 days. Overall efficacy was 77%. The efficacy against the various species was 93% forCandida parapsilosis, 50% forCandida glabrata, and 82% forCandida tropicalis. In conclusion, fluconazole is effective against the most commonnonalbicans Candida spp., although higher doses may be required for infections caused byCandida glabrata. Infections caused byCandida krusei should not be treated with fluconazole. Springer-Verlag, 1996 European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/3(1996-03-01), 238-242 0934-9723 15:3<238 1996 15 10096 https://doi.org/10.1007/BF01591361 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01591361 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- van't Wout J. Department of Infectious Diseases, University Hospital Leiden, Building 1, C5P, PO Box 9600, 2300, RC Leiden, The Netherlands aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/3(1996-03-01), 238-242 0934-9723 15:3<238 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer