caa a22 4500 477071112 CHVBK 20180405111425.0 cr unu---uuuuu 170330e19960801xx s 000 0 eng 10.1007/BF01691161 doi (NATIONALLICENCE)springer-10.1007/BF01691161 In vitro susceptibility of pneumococci to trovafloxacin, penicillin G, and other antimicrobial agents in the Czech Republic and Slovakia [Elektronische Daten] [P. Urbášková, J. Trupl, H. Hupková, P. Appelbaum, M. Jacobs] The in vitro activity of the new naphthyridone trovafloxacin (CP 99,219) was compared with those of penicillin G and six other agents (cefpodoxime, erythromycin, azithromycin, clindamycin, ciprofloxacin, and sparfloxacin) against 316 penicillin-susceptible and -resistant pneumococci isolated in the former Czechoslovakia. Trovafloxacin was very active against strains ofStreptococcus pneumoniae (MIC50 and MIC90 0.25 Μg/ml). Ciprofloxacin was less active (MIC50 1.0 Μg/ml, MIC90 2.0 (Μg/ml), and MICs of sparfloxacin were between those of trovafloxacin and ciprofloxacin (MIC50 and MIC90 both 0.5 Μg/ml). MICs of cefpodoxime, erythromycin, azithromycin, and clindamycin were higher for strains intermediately resistant or resistant to penicillin than for penicillin-susceptible strains. Springer-Verlag, 1996 Urbášková P. National Reference Laboratory for Antibiotics, National Institute of Public Health, Srobarova 48, 100 42, Prague, Czech Republic aut Trupl J. Postgraduate Medical School, Bratislava, Slovak Republic aut Hupková H. Postgraduate Medical School, Bratislava, Slovak Republic aut Appelbaum P. Departments of Pathology and Clinical Microbiology, Hershey Medical Center, 17033, Hershey, Pennsylvania, USA aut Jacobs M. Case Western Reserve University, 44106, Cleveland, Ohio, USA aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/8(1996-08-01), 686-688 0934-9723 15:8<686 1996 15 10096 https://doi.org/10.1007/BF01691161 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691161 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Urbášková P. National Reference Laboratory for Antibiotics, National Institute of Public Health, Srobarova 48, 100 42, Prague, Czech Republic aut NATIONALLICENCE 700 1- Trupl J. Postgraduate Medical School, Bratislava, Slovak Republic aut NATIONALLICENCE 700 1- Hupková H. Postgraduate Medical School, Bratislava, Slovak Republic aut NATIONALLICENCE 700 1- Appelbaum P. Departments of Pathology and Clinical Microbiology, Hershey Medical Center, 17033, Hershey, Pennsylvania, USA aut NATIONALLICENCE 700 1- Jacobs M. Case Western Reserve University, 44106, Cleveland, Ohio, USA aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/8(1996-08-01), 686-688 0934-9723 15:8<686 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer