caa a22 4500 477071155 CHVBK 20180405111426.0 cr unu---uuuuu 170330e19960801xx s 000 0 eng 10.1007/BF01691148 doi (NATIONALLICENCE)springer-10.1007/BF01691148 Molecular epidemiological characteristics of pneumococcal meningitis in children [Elektronische Daten] [R. Kornelisse, M. Sluijter, L. Spanjaard, P. Hermans, R. de Groot] The molecular epidemiological characteristics of pneumococcal meningitis in children were studied. Pneumococcal isolates were characterized by serotyping and two genotyping methods, BOX fingerprinting and restriction fragment end labeling, to evaluate whether clonal strains were present within the serotypes or serogroups. During a 17-year period, 68 children admitted to the Sophia Children's Hospital were diagnosed with meningitis due toStreptococcus pneumoniae. Pneumococcal isolates from 44 patients were still available for analysis. All strains were susceptible to penicillin. Serotypes/ serogroups 14,19, 6, and 18 represented 56% of all isolates. The results of the molecular typing methods demonstrate the absence of clonal relatedness between isolates from patients with pneumococcal meningitis. Springer-Verlag, 1996 Kornelisse R. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut Sluijter M. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut Spanjaard L. Netherlands Reference Laboratory for Bacterial Meningitis, University of Amsterdam/National Institute of Public Health and the Environment, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands aut Hermans P. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut de Groot R. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/8(1996-08-01), 635-638 0934-9723 15:8<635 1996 15 10096 https://doi.org/10.1007/BF01691148 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691148 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kornelisse R. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Sluijter M. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Spanjaard L. Netherlands Reference Laboratory for Bacterial Meningitis, University of Amsterdam/National Institute of Public Health and the Environment, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Hermans P. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- de Groot R. Department of Pediatrics, Sophia Children's Hospital/University Hospital Rotterdam, Dr. Molewaterplein 60, 3015, GJ Rotterdam, The Netherlands aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/8(1996-08-01), 635-638 0934-9723 15:8<635 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer