caa a22 4500 477071201 CHVBK 20180405111426.0 cr unu---uuuuu 170330e19960801xx s 000 0 eng 10.1007/BF01691162 doi (NATIONALLICENCE)springer-10.1007/BF01691162 In vitro activity of trovafloxacin in combination with ceftazidime, meropenem, and amikacin [Elektronische Daten] [D. Milatovic, C. Wallrauch] The in vitro activity of trovafloxacin alone and in combination with ceftazidime, meropenem, and amikacin was studied by determining the minimal inhibitory concentrations (MICs) for 111 gram-negative and 71 gram-positive bacteria. In addition, the synergy of these combinations against 46 strains of gram-negative and gram-positive organisms was studied by checkerboard titration and time-kill kinetics. Trovafloxacin exhibited excellent in vitro activity against all strains tested. Synergism was observed in 17% of the gram-negative strains and in 32% of the gram-positive strains. No antagonism was observed with any of the combinations tested. Springer-Verlag, 1996 Milatovic D. Institute of Medical Microbiology, Immunology and Hygiene, Trogerstr. 32, 81675, Munich, Germany aut Wallrauch C. Institute of Medical Microbiology, Immunology and Hygiene, Trogerstr. 32, 81675, Munich, Germany aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/8(1996-08-01), 688-693 0934-9723 15:8<688 1996 15 10096 https://doi.org/10.1007/BF01691162 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691162 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Milatovic D. Institute of Medical Microbiology, Immunology and Hygiene, Trogerstr. 32, 81675, Munich, Germany aut NATIONALLICENCE 700 1- Wallrauch C. Institute of Medical Microbiology, Immunology and Hygiene, Trogerstr. 32, 81675, Munich, Germany aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/8(1996-08-01), 688-693 0934-9723 15:8<688 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer