caa a22 4500 47707166X CHVBK 20180405111427.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/BF01691218 doi (NATIONALLICENCE)springer-10.1007/BF01691218 Role of granulocyte colony-stimulating factor in the treatment of mucormycosis [Elektronische Daten] [B. Şahin, S. Paydaş, E. Coşar, K. Biçakçi, B. Hazar] Several problems in the management of life-threatening mucormycosis remain unresolved, necessitating new methods of management. Four patients with histopathologically proven rhinocerebral mucormycosis were treated with high cumulative doses of granulocyte colony-stimulating factor (G-CSF). All had multiple predisposing factors for mucormycosis, particularly leukemia and neutropenia. Two patients refractory to fluconazole therapy were treated with liposomal amphotericin B. The improvement in clinical manifestations was closely related to neutrophil recovery, and all patients were alive at the end of therapy. In addition to surgical debridement and antifungal therapy, G-CSF seems to have played a role in their survival. Springer-Verlag, 1996 Şahin B. Department of Oncology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut Paydaş S. Department of Oncology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut Coşar E. Department of Pathology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut Biçakçi K. Department of Radiology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut Hazar B. Department of Oncology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/11(1996-11-01), 866-869 0934-9723 15:11<866 1996 15 10096 https://doi.org/10.1007/BF01691218 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01691218 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Şahin B. Department of Oncology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut NATIONALLICENCE 700 1- Paydaş S. Department of Oncology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut NATIONALLICENCE 700 1- Coşar E. Department of Pathology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut NATIONALLICENCE 700 1- Biçakçi K. Department of Radiology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut NATIONALLICENCE 700 1- Hazar B. Department of Oncology, Çukurova University, Faculty of Medicine, 01330, Balcalì-Adana, Turkey aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology and Infectious Diseases Springer-Verlag 15/11(1996-11-01), 866-869 0934-9723 15:11<866 1996 15 10096 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer