caa a22 4500 477071996 CHVBK 20180405111428.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00051125 doi (NATIONALLICENCE)springer-10.1007/BF00051125 Usefulness of diltiazem in the acute management of supraventricular tachyarrhythmias in the elderly [Elektronische Daten] [Alain Millaire, Olivier Leroy, Pascal de Groote, Charles Santré, Gérard Ducloux] Summary: Acute management of supraventricular tachyarrhythmias is often difficult in elderly patients. Diltiazem was given intravenously (loading dose of 0.25 mg/kg over 2 minutes followed by a 4 mg/kg/24 hr infusion) in 37 elderly patients (mean age 70 years, range 60-91). Fifteen out of the 37 patients (41%) had left ventricular cardiac disease, 12 (32%) had cor pulmonale, and 10 (27%) had no obvious cardiac disease. Hemodynamic tolerance of the supraventricular tachyarrhythmia was poor in 12 patients. A good result was defined as a return to sinus rhythm after bolus or infusion, or as a slowing of the ventricular rate (VR) to less than 100 beats/min. Of the 23 patients in atrial fibrillation, about half reverted to sinus rhythm after diltiazem, and in most of the others the ventricular rate decreased to less than 100 beats/min. Side effects occurred in 10 patients (bradycardia in 6, cutaneous rash in 2, hypotension in 2). They rapidly reversed after cessation of diltiazem. They were responsible for 2 out of the 5 poor results. Thus, diltiazem appeared effective and safe when used carefully in elderly patients with supraventricular tachyarrhythmia. Kluwer Academic Publishers, 1996 clinical trial nationallicence supraventricular tachyarrhythmias nationallicence diltiazem nationallicence Millaire Alain Division of Cardiology, University Hospital, Lille, France aut Leroy Olivier Division of Reanimation, University Department of Infectious Diseases, Tourcoing, France aut de Groote Pascal Division of Cardiology, University Hospital, Lille, France aut Santré Charles Division of Reanimation, University Department of Infectious Diseases, Tourcoing, France aut Ducloux Gérard Division of Cardiology, University Hospital, Lille, France aut Cardiovascular Drugs and Therapy Kluwer Academic Publishers 10/1(1996-03-01), 11-16 0920-3206 10:1<11 1996 10 10557 https://doi.org/10.1007/BF00051125 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00051125 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Millaire Alain Division of Cardiology, University Hospital, Lille, France aut NATIONALLICENCE 700 1- Leroy Olivier Division of Reanimation, University Department of Infectious Diseases, Tourcoing, France aut NATIONALLICENCE 700 1- de Groote Pascal Division of Cardiology, University Hospital, Lille, France aut NATIONALLICENCE 700 1- Santré Charles Division of Reanimation, University Department of Infectious Diseases, Tourcoing, France aut NATIONALLICENCE 700 1- Ducloux Gérard Division of Cardiology, University Hospital, Lille, France aut NATIONALLICENCE 773 0- Cardiovascular Drugs and Therapy Kluwer Academic Publishers 10/1(1996-03-01), 11-16 0920-3206 10:1<11 1996 10 10557 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer