caa a22 4500 477074243 CHVBK 20180405111435.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/BF02252850 doi (NATIONALLICENCE)springer-10.1007/BF02252850 Mathemathical model of Ca2+ diffusion and buffering in extracellular solution after Ca2+ extrusion from a spherical cell [Elektronische Daten] [P. Belan, E. Saftenku] A mathematical model evaluating the changes in the concentration of free extracellular calcium ([Ca2+]) as a function of time and radial distance from a spherical cell following uniform calcium release across its external membrane was developed. The space of extracellular solution was represented as concentric shells of uniform thickness. Two simplified approaches were used, which allowed us to describe calcium diffusion and buffering in each extracellular shell by only a single differential equation. The possibility of simulating the spatio-temporal [Ca2+] distribution in the case of uniformly located calcium pumps was demonstrated. Developed for pancreatic acinar cells, our model can be also used for studying ion release from other cells under similar experimental conditions and for reconstruction of ion fluxes in the presence of different fluorescent dyes. Plenum Publishing Corporation, 1997 Belan P. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut Saftenku E. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut Neurophysiology Kluwer Academic Publishers-Plenum Publishers 28/6(1996-11-01), 187-192 0090-2977 28:6<187 1996 28 11062 https://doi.org/10.1007/BF02252850 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02252850 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Belan P. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut NATIONALLICENCE 700 1- Saftenku E. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut NATIONALLICENCE 773 0- Neurophysiology Kluwer Academic Publishers-Plenum Publishers 28/6(1996-11-01), 187-192 0090-2977 28:6<187 1996 28 11062 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer