caa a22 4500 477074251 CHVBK 20180405111435.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/BF02252857 doi (NATIONALLICENCE)springer-10.1007/BF02252857 Sachenko V. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut Effects of blockade of noradrenergic and serotonergic transmission in the CM-Pf complex on neuronal activity in the motor thalamus in cats [Elektronische Daten] [V. Sachenko] Effects of injections of blockers of the monoaminergic receptor structures into thecentrum medianum-nucl. parafascicularis (CM-Pf) on the activity of neurons in the motor thalamic nuclei (VA-VL) were studied in chronic experiments on awake cats. The animals were trained to perform an operant placing reflex by the forelimb. Injection of aβ-adrenoblocker, anapriline, into theCM-Pf resulted in enhancement of background activity of neurons of the motor thalamus and facilitation of their spike responses related to conditioned and unconditioned reflex movements. Application of a blocker of serotonin receptors, lysergoamide, evoked opposite changes in the neuronal activity in theVA-VL nuclei: depression of background activity, facilitation of inhibitory processes, and suppression of evoked activity related to conditioned and unconditioned movements. It is supposed that the monoaminergic system of thelocus coeruleus exerts a suppressing influence on the motor thalamus via theCM-Pf complex, while the system of the raphe nuclei facilitates motor thalamic structures. Plenum Publishing Corporation, 1997 Neurophysiology Kluwer Academic Publishers-Plenum Publishers 28/6(1996-11-01), 240-245 0090-2977 28:6<240 1996 28 11062 https://doi.org/10.1007/BF02252857 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02252857 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Sachenko V. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut NATIONALLICENCE 773 0- Neurophysiology Kluwer Academic Publishers-Plenum Publishers 28/6(1996-11-01), 240-245 0090-2977 28:6<240 1996 28 11062 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer