caa a22 4500 477074308 CHVBK 20180405111435.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF02262771 doi (NATIONALLICENCE)springer-10.1007/BF02262771 Laminar distribution of the cells of origin of the spinocerebral pathways involved in nociceptive transmission and pain modulation in the rat [Elektronische Daten] [G. Kayalioglu, N. Hariri, F. Govsa, B. Erdem, G. Peker, V. Maiskii] The laminar distribution of spinomesencephalic, spinothalamic, and spinotelencephalic tract neurons, and the pattern of axonal collateralization in these spinocerebral pathways were studied in the rat by means of retrograde double-labelling of the cells with fluorescent dyes Fluoro-Gold and Primuline O. We found that sources of spinocerebral pathways to the analgesic brainstem centers, as well to thenucl. accumbens and septal nuclei, were mixed together in the marginal zone (lamina I, by Rexed), in the deep dorsal horn (laminae IV-VI), in the area around the central canal (lamina X), and within the lateral spinal nucleus. At the same time, all the above pathways retain their own specific projection fields. Thus, these spinocerebral projections could be characterized as extensive, but not diffuse. We propose that the main effect of activation of the direct spinal inputs to the limbic system is an increase in nociceptive sensitivity, but not a suppression of nocicptive transmission at the the spinal cord level. Plenum Publishing Corporation, 1997 Kayalioglu G. School of Medicine, Ege University, Izmir, Turkey aut Hariri N. School of Medicine, Ege University, Izmir, Turkey aut Govsa F. School of Medicine, Ege University, Izmir, Turkey aut Erdem B. School of Medicine, Ege University, Izmir, Turkey aut Peker G. School of Medicine, Ege University, Izmir, Turkey aut Maiskii V. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut Neurophysiology Kluwer Academic Publishers-Plenum Publishers 28/2-3(1996-03-01), 111-118 0090-2977 28:2-3<111 1996 28 11062 https://doi.org/10.1007/BF02262771 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02262771 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kayalioglu G. School of Medicine, Ege University, Izmir, Turkey aut NATIONALLICENCE 700 1- Hariri N. School of Medicine, Ege University, Izmir, Turkey aut NATIONALLICENCE 700 1- Govsa F. School of Medicine, Ege University, Izmir, Turkey aut NATIONALLICENCE 700 1- Erdem B. School of Medicine, Ege University, Izmir, Turkey aut NATIONALLICENCE 700 1- Peker G. School of Medicine, Ege University, Izmir, Turkey aut NATIONALLICENCE 700 1- Maiskii V. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine aut NATIONALLICENCE 773 0- Neurophysiology Kluwer Academic Publishers-Plenum Publishers 28/2-3(1996-03-01), 111-118 0090-2977 28:2-3<111 1996 28 11062 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer