caa a22 4500 47708205X CHVBK 20180405111452.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/BF01922411 doi (NATIONALLICENCE)springer-10.1007/BF01922411 Induction of neovascularization in vivo by glycerol [Elektronische Daten] [L. Diaz-Flores, R. Gutterrez, H. Varela] Glycerol, injected into a site between the femoral vessels of the rat, induced neovascularization, both from the preexisting microcirculation and from the side of the femoral vein facing the artery-vein interstitium where the glycerol was administered. The use of glycerol together with a known angiogenic substance (PGE2) did not modify the neocapillary density (NCD) obtained with glycerol alone. In contrast, the lower level of NCD achieved with an acylglycerol (triacetylglycerol) was increased when the latter was associated with PGE2. Values reached were similar to, but never higher than, those for glycerol alone, or combined with PGE2. The results suggest that glycerol and some substances containing glycerol, amongst which 1-butyrylglycerol has been previously considered1, may stimulate angiogenesis by a direct or indirect mechanism of action. Birkhäuser Verlag Basel, 1996 Angiogenesis nationallicence glycerol nationallicence acylglycerols nationallicence endothelial cells nationallicence smooth muscle cells nationallicence veins nationallicence microcirculation nationallicence neovascularization nationallicence Diaz-Flores L. Department of Anatomy and Pathology, Faculty of Medicine, University of La Laguna, 38320, Tenerife, Canary Islands, (Spain) aut Gutterrez R. Department of Anatomy and Pathology, Faculty of Medicine, University of La Laguna, 38320, Tenerife, Canary Islands, (Spain) aut Varela H. Department of Anatomy and Pathology, Faculty of Medicine, University of La Laguna, 38320, Tenerife, Canary Islands, (Spain) aut Experientia Birkhäuser-Verlag 52/1(1996-01-01), 25-30 0014-4754 52:1<25 1996 52 18 https://doi.org/10.1007/BF01922411 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01922411 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Diaz-Flores L. Department of Anatomy and Pathology, Faculty of Medicine, University of La Laguna, 38320, Tenerife, Canary Islands, (Spain) aut NATIONALLICENCE 700 1- Gutterrez R. Department of Anatomy and Pathology, Faculty of Medicine, University of La Laguna, 38320, Tenerife, Canary Islands, (Spain) aut NATIONALLICENCE 700 1- Varela H. Department of Anatomy and Pathology, Faculty of Medicine, University of La Laguna, 38320, Tenerife, Canary Islands, (Spain) aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/1(1996-01-01), 25-30 0014-4754 52:1<25 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer