caa a22 4500 477082343 CHVBK 20180405111453.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF01969731 doi (NATIONALLICENCE)springer-10.1007/BF01969731 Inhibition of lipid peroxidation by diterpenoid from Podocarpus nagi [Elektronische Daten] [H. Haraguchi, H. Ishikawa, S. Sakai, B. Ying, I. Kubo] A diterpenoid, totarol (1), fromPodocarpus nagi was evaluated as an antioxidant. This diterpenoid inhibited autoxidation of linoleic acid. Mitochondrial and microsomal lipid peroxidation induced by Fe(III)-ADP/NADH or Fe(III)-ADP/NADPH were also inhibited. Nagilactone E (2), a norditerpene lactone isolated from the same source, had no antioxidative activity. Furthermore, totarol protected red cells against oxidative hemolysis. This diterpene was shown to be effective in protecting biological systems against oxidative stresses. Birkhäuser Verlag, 1996 Podocarpus nagi nationallicence totarol nationallicence lipid peroxidation nationallicence oxidative stress nationallicence Haraguchi H. Faculty of Engineering, Fukuyama University, Gakuen-cho, 729-02, Fukuyama, (Japan) aut Ishikawa H. Faculty of Engineering, Fukuyama University, Gakuen-cho, 729-02, Fukuyama, (Japan) aut Sakai S. Faculty of Engineering, Fukuyama University, Gakuen-cho, 729-02, Fukuyama, (Japan) aut Ying B. Department of Environmental Science, Policy and Management, University of California, 94720-3112, Berkeley, California, USA aut Kubo I. Department of Environmental Science, Policy and Management, University of California, 94720-3112, Berkeley, California, USA aut Experientia Birkhäuser-Verlag 52/6(1996-06-01), 573-576 0014-4754 52:6<573 1996 52 18 https://doi.org/10.1007/BF01969731 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01969731 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Haraguchi H. Faculty of Engineering, Fukuyama University, Gakuen-cho, 729-02, Fukuyama, (Japan) aut NATIONALLICENCE 700 1- Ishikawa H. Faculty of Engineering, Fukuyama University, Gakuen-cho, 729-02, Fukuyama, (Japan) aut NATIONALLICENCE 700 1- Sakai S. Faculty of Engineering, Fukuyama University, Gakuen-cho, 729-02, Fukuyama, (Japan) aut NATIONALLICENCE 700 1- Ying B. Department of Environmental Science, Policy and Management, University of California, 94720-3112, Berkeley, California, USA aut NATIONALLICENCE 700 1- Kubo I. Department of Environmental Science, Policy and Management, University of California, 94720-3112, Berkeley, California, USA aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/6(1996-06-01), 573-576 0014-4754 52:6<573 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer