caa a22 4500 477082548 CHVBK 20180405111454.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF01938880 doi (NATIONALLICENCE)springer-10.1007/BF01938880 The modulus of elasticity of lobster aorta microfibrils [Elektronische Daten] [C. McConnell, G. Wright, M. DeMont] The presence of elastic fibres in the extracellular matrix (ECM) provides physiologically important elastic properties for many tissues. Until recently, microfibrils, one component of the ECM, were thought primarily to serve as a scaffolding on which elastin is deposited during development to form elaunin fibres [1]. The most prominent protein that forms mammalian microfibrils is fibrillin. It is known that mutations in the fibrillin gene cause a heterogenous connective tissue disease called marfan syndrome [2], so information on mechanical properties of microfibrils or their role in tissue function would be useful. Microfibrils are also found in the ECM of some invertebrate tissues, and there is growing evidence that the protein forming the structure is homologous to mammalian fibrillin [3, 4]. It has been shown that the microfibril-based arterial wall of the lobster has viscoelastic properties [5], and we have now utilized this primitive artery to measure the modulus of elasticity of microfibrils. It is similar to that of the rubber-like protein elastin. Birkhäuser Verlag, 1996 Artery nationallicence aorta nationallicence elastin nationallicence extracellular matrix nationallicence lobster nationallicence Marfan syndrome nationallicence microfibrils nationallicence McConnell C. Biology Department, St. Francis Xavier University, P.O. Box 5000, B2G 2W5, Antigonish, Nova Scotia, Canada aut Wright G. Department of Anatomy and Physiology, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, C1A 4P3, Charlottetown, Prince Edward Island, Canada aut DeMont M. Biology Department, St. Francis Xavier University, P.O. Box 5000, B2G 2W5, Antigonish, Nova Scotia, Canada aut Experientia Birkhäuser-Verlag 52/9(1996-09-01), 918-921 0014-4754 52:9<918 1996 52 18 https://doi.org/10.1007/BF01938880 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01938880 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McConnell C. Biology Department, St. Francis Xavier University, P.O. Box 5000, B2G 2W5, Antigonish, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Wright G. Department of Anatomy and Physiology, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, C1A 4P3, Charlottetown, Prince Edward Island, Canada aut NATIONALLICENCE 700 1- DeMont M. Biology Department, St. Francis Xavier University, P.O. Box 5000, B2G 2W5, Antigonish, Nova Scotia, Canada aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/9(1996-09-01), 918-921 0014-4754 52:9<918 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer