caa a22 4500 477082750 CHVBK 20180405111454.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/BF01925586 doi (NATIONALLICENCE)springer-10.1007/BF01925586 The phorbol ester TPA induces metamorphosis in Red Sea coral planulae (Cnidaria: Anthozoa) [Elektronische Daten] [G. Henning, D. Hofmann, Y. Benayahu] Controlled experiments on the metamorphosis of marine invertebrate larvae require artificial inducers. These inducers can be used for studying the involvement of known signal transduction pathways in settlement and metamorphosis. The ability of the tumor-promoting phorbol ester TPA (12-O-tetradecanoylphorbol-13-acetate) to induce metamorphosis in planulae of the Red Sea soft coral speciesHeteroxenia fuscescens, Xenia umbellata, Dendronephthya hemprichii, Litophyton arboreum andParerythropodium fulvum fulvum, and the stony coralStylophora pistillata, was examined by using various concentrations of TPA. The chemical induced metamorphosis in all six species. The effect was unspecific and concentration-related. For all the corals except forX. umbellata the highest mean percentages of metamorphosis were obtained with 8.1×10−7-10−9 M TPA. ForX. umbellata, the percentage of metamorphosis was lower, and was obtained within a wider TPA concentration range. The present results, along with previous studies on Hydrozoa and Scyphozoa, demonstrate that TPA is the first common artificial inducer for these classes of Cnidaria. TPA is known to activate the enzyme protein kinase C (PKC) and therefore plays an important role in studying the phosphatidylinositol signal transduction system. Evidence for the involvement of this pathway in triggering metamorphosis has already been reported for Hydrozoa and Scyphozoa. Our results suggest that PKC is also involved in initiating metamorphosis in Anthozoa. Birkhäuser Verlag, 1996 Red Sea nationallicence Cnidaria nationallicence Anthozoa nationallicence coral planulae nationallicence induction of metamorphosis nationallicence phorbol ester nationallicence protein kinase C nationallicence Henning G. Department of Zoology and Parasitology, Ruhr-University Bochum, D-44780, Bochum, (Germany) aut Hofmann D. Department of Zoology and Parasitology, Ruhr-University Bochum, D-44780, Bochum, (Germany) aut Benayahu Y. Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat-Aviv, 69978, Tel Aviv, (Israel) aut Experientia Birkhäuser-Verlag 52/7(1996-07-01), 744-749 0014-4754 52:7<744 1996 52 18 https://doi.org/10.1007/BF01925586 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01925586 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Henning G. Department of Zoology and Parasitology, Ruhr-University Bochum, D-44780, Bochum, (Germany) aut NATIONALLICENCE 700 1- Hofmann D. Department of Zoology and Parasitology, Ruhr-University Bochum, D-44780, Bochum, (Germany) aut NATIONALLICENCE 700 1- Benayahu Y. Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat-Aviv, 69978, Tel Aviv, (Israel) aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/7(1996-07-01), 744-749 0014-4754 52:7<744 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer