caa a22 4500 477082947 CHVBK 20180405111455.0 cr unu---uuuuu 170330e19961201xx s 000 0 eng 10.1007/BF01952101 doi (NATIONALLICENCE)springer-10.1007/BF01952101 The cytosolic and membrane components required for peroxisomal protein import [Elektronische Daten] [S. Terlecky, W. Nuttley, S. Subramani] Peroxisomes are vital intracellular organelles which house enzymes involved in a variety of metabolic pathways. The large number of human disorders associated with flawed peroxisome biogenesis emphasizes the importance of protein targeting to, and translocation across, the peroxisomal membrane. This brief review will summarize some of the emerging themes of peroxisomal protein import, specifically addressing the targeting signals possessed by constituent proteins, as well as the cytosolic, membrane and luminal components of the import machinery. Although a detailed understanding of the molecular mechanisms of peroxisomal protein import is not yet available, remarkable progress has been made in the field in recent years. An overview of these advances will be presented. Birkhäuser Verlag, 1996 Peroxisomes nationallicence biogenesis nationallicence targeting nationallicence receptors nationallicence import nationallicence heat shock proteins nationallicence Terlecky S. Department of Biology, University of California, San Diego, 9500 Gilman Drive, 92093-0322, La Jolla, California, USA aut Nuttley W. Department of Biology, University of California, San Diego, 9500 Gilman Drive, 92093-0322, La Jolla, California, USA aut Subramani S. Department of Biology, University of California, San Diego, 9500 Gilman Drive, 92093-0322, La Jolla, California, USA aut Experientia Birkhäuser-Verlag 52/12(1996-12-01), 1050-1054 0014-4754 52:12<1050 1996 52 18 https://doi.org/10.1007/BF01952101 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01952101 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Terlecky S. Department of Biology, University of California, San Diego, 9500 Gilman Drive, 92093-0322, La Jolla, California, USA aut NATIONALLICENCE 700 1- Nuttley W. Department of Biology, University of California, San Diego, 9500 Gilman Drive, 92093-0322, La Jolla, California, USA aut NATIONALLICENCE 700 1- Subramani S. Department of Biology, University of California, San Diego, 9500 Gilman Drive, 92093-0322, La Jolla, California, USA aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/12(1996-12-01), 1050-1054 0014-4754 52:12<1050 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer