caa a22 4500 477083102 CHVBK 20180405111455.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF01920710 doi (NATIONALLICENCE)springer-10.1007/BF01920710 Effects of progesterone and estradiol benzoate on superoxide dismutase activity in the brain of male rats [Elektronische Daten] [S. Pajović, Z. Saičić, M. Spasić, V. Petrović, J. Martinović] The activities of mitochondrial, manganese-containing superoxide dismutase (MnSOD) and cytoplasmic, copper-zinc-containing superoxide dismutase (CuZnSOD) were measured in subcellular fractions of whole brain homogenates prepared from intact and gonadectomized (GDX) male rats, untreated or treated subcutaneously (sc) with a single dose of 2 mg progesterone (P) and/or 5 μg estradiol benzoate (EB). Neither MnSOD nor CuZnSOD was affected by the removal of the testes. Similarly, CuZnSOD activity was steady following systemic administration of P and/or EB to intact and GDX animals 2 h or 24 h prior to sacrifice. On the other hand, both P and EB suppressed MnSOD in the brain of either intact or GDX rats. These results suggest involvement of P and EB in the control of MnSOD activity in the brain of male rats. Birkhäuser Verlag, 1996 Superoxide dismutase nationallicence brain nationallicence progesterone nationallicence estradiol nationallicence rats nationallicence Pajović S. Laboratory for Molecular Biology and Endocrinology, Vinča Institute for Nuclear Sciences, P.O. Box 522, YU-11001, Belgrade aut Saičić Z. Department of Physiology, Sinisa Stanković Institute for Biological Research, 29 Novembra 142, YU-11060, Belgrade, Yugoslavia aut Spasić M. Department of Physiology, Sinisa Stanković Institute for Biological Research, 29 Novembra 142, YU-11060, Belgrade, Yugoslavia aut Petrović V. Department of Physiology, Sinisa Stanković Institute for Biological Research, 29 Novembra 142, YU-11060, Belgrade, Yugoslavia aut Martinović J. Laboratory for Molecular Biology and Endocrinology, Vinča Institute for Nuclear Sciences, P.O. Box 522, YU-11001, Belgrade aut Experientia Birkhäuser-Verlag 52/3(1996-03-01), 221-224 0014-4754 52:3<221 1996 52 18 https://doi.org/10.1007/BF01920710 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01920710 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pajović S. Laboratory for Molecular Biology and Endocrinology, Vinča Institute for Nuclear Sciences, P.O. Box 522, YU-11001, Belgrade aut NATIONALLICENCE 700 1- Saičić Z. Department of Physiology, Sinisa Stanković Institute for Biological Research, 29 Novembra 142, YU-11060, Belgrade, Yugoslavia aut NATIONALLICENCE 700 1- Spasić M. Department of Physiology, Sinisa Stanković Institute for Biological Research, 29 Novembra 142, YU-11060, Belgrade, Yugoslavia aut NATIONALLICENCE 700 1- Petrović V. Department of Physiology, Sinisa Stanković Institute for Biological Research, 29 Novembra 142, YU-11060, Belgrade, Yugoslavia aut NATIONALLICENCE 700 1- Martinović J. Laboratory for Molecular Biology and Endocrinology, Vinča Institute for Nuclear Sciences, P.O. Box 522, YU-11001, Belgrade aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/3(1996-03-01), 221-224 0014-4754 52:3<221 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer