caa a22 4500 477083145 CHVBK 20180405111455.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF01920707 doi (NATIONALLICENCE)springer-10.1007/BF01920707 Ameen A. 120A Ashley Forest Drive, 27514, Chapel Hill, North Carolina, USA aut On the physiology of metazoa [Elektronische Daten] [A. Ameen] The problem of integration and control of the various processes of the metazoan organism is a major challenge to the physiologist. The traditional research strategy in dealing with the problem is neuron-oriented and its roots extend back into the last century when knowledge of hormones was lacking. In the present article, the traditional strategy is analyzed in the light of available data and its logical basis is questioned. Different levels of communication are supposed to occur in the animal or human body. Circulating hormones are responsible for the highest level of communication that occurs between organs or tissues. The central concept in the article is that regulation of circulating hormones constitutes a higher level of control relative to regulation of intercellular hormones. This is regardless of whether the latter occurs in the nervous system or elsewhere. The approach is utilized in defining the mechanism that integrates and controls the part processes of the body. The mechanism is defined as endothelial; the vascular endothelial system is the controlling part and the nervous system is one of the subordinate parts. Thanks to the new approach, meaningful biological explanations of major psychiatric disorders are now possible. Birkhäuser Verlag, 1996 Pulmonary endothelium nationallicence angiotensins nationallicence enkephalins nationallicence phenylethylamine nationallicence hallucinogens nationallicence schizophrenia nationallicence β-carbolines nationallicence affective and sexual behavior nationallicence Experientia Birkhäuser-Verlag 52/3(1996-03-01), 189-211 0014-4754 52:3<189 1996 52 18 https://doi.org/10.1007/BF01920707 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01920707 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Ameen A. 120A Ashley Forest Drive, 27514, Chapel Hill, North Carolina, USA aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/3(1996-03-01), 189-211 0014-4754 52:3<189 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer