caa a22 4500 477083951 CHVBK 20180405111457.0 cr unu---uuuuu 170330e19960401xx s 000 0 eng 10.1007/BF01919536 doi (NATIONALLICENCE)springer-10.1007/BF01919536 Effect of various stressors on the levels of lipid peroxide, antioxidants and Na+, K+-ATPase actrivity in rat brain [Elektronische Daten] [A. Shaheen, A. Abd El-Fattah, M. Gad] The level of malondialdehyde (MDA), an index of lipid peroxidation, and the antioxidants superoxide dismutase (SOD) and glutathione (GSH), as well as the activity of Na+, K+-ATPase, were assessed in whole rat brain after immobilization, anemic hypoxia (NaNO2) and 72 h starvation. The effect of these stressors on plasma glucose and corticosterone levels was also observed. Hypoxia and starvation stimulated the lipidj peroxide formation in braini as indicated by an increase in the level of MDA, being higher after starvation than hypoxia. Brain SOD activity was also increased in response to hypoxia and starvation while GSH content was only diminished ini hypoxia. However, neither MDA nor antioxidants were affected by immobilization. On the other hand, the activity of brain Na+, K+-ATPase was significantly increased by immobilization and hypoxia but decreased in starvation. A similar pattern of change was also observed in plasma glucose and corticosterone levels in response to these stressors. These results elucidate differences in the biochemical response of animals towards various types of stress, with increased lipid peroxide formation in hypoxia and starvation. Birkhäuser Verlag, 1996 Strees nationallicence hypoxia nationallicence immobilization nationallicence starvation nationallicence lipid peroxide nationallicence antioxidants nationallicence Na+-ATPase nationallicence Shaheen A. Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt) aut Abd El-Fattah A. Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt) aut Gad M. Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt) aut Experientia Birkhäuser-Verlag 52/4(1996-04-01), 336-339 0014-4754 52:4<336 1996 52 18 https://doi.org/10.1007/BF01919536 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01919536 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shaheen A. Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt) aut NATIONALLICENCE 700 1- Abd El-Fattah A. Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt) aut NATIONALLICENCE 700 1- Gad M. Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt) aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/4(1996-04-01), 336-339 0014-4754 52:4<336 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer