caa a22 4500 477084346 CHVBK 20180405111458.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/BF01923352 doi (NATIONALLICENCE)springer-10.1007/BF01923352 Characterization and localization of the rat, mouse and human testicular phosphatidylethanolamine binding protein [Elektronische Daten] [N. Seddiqi, N. Segretain, S. Bucquoy, C. Pineau, B. Jégou, P. Jollès, F. Schoentgen] A cytosolic 23kDa protein was initially puified from bovine brain and shown to bind phosphatidylethanolamine. Later, it was also characterized in rat and human brain, and it is now known to be widespread, having been found in numerous tisues in several species. Here, we report the high level of mRNA and phosphatidyl ethanolamine binding protein expression in rat testis and to a lesser extent mouse testis. In human testis, although it was not detectable by Northern blot analysis, the mRNA was shown be present when PCR amplificatin was performed. Immunohistochemical experiments revealed that the testicular phosphatidylethanolamine binding protein (tPBP) is principally expressed in the elongated spermatids of both rat and mouse testis. This finding, and the association of tPBP with cellular membranes, suggest its possible implication in membrane remodelling during spermatid maturation. Birkhäuser Verlag Basel, 1996 21-23kDa protein nationallicence phosphatidylethanolamine binding protein nationallicence sperimatogenesis nationallicence testis development nationallicence Seddiqi N. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut Segretain N. Laboratorie d'embyrologie CHU Paris-Ouest, Université René Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut Bucquoy S. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut Pineau C. Groupe d'étude de la reproduction chez le mâle, INSERM CJF 91-04, Campus de Beaulieu, Avenue du Général Leclerc, F-35042, Rennes Cedex, (France) aut Jégou B. Groupe d'étude de la reproduction chez le mâle, INSERM CJF 91-04, Campus de Beaulieu, Avenue du Général Leclerc, F-35042, Rennes Cedex, (France) aut Jollès P. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut Schoentgen F. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut Experientia Birkhäuser-Verlag 52/2(1996-02-01), 101-110 0014-4754 52:2<101 1996 52 18 https://doi.org/10.1007/BF01923352 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01923352 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Seddiqi N. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut NATIONALLICENCE 700 1- Segretain N. Laboratorie d'embyrologie CHU Paris-Ouest, Université René Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut NATIONALLICENCE 700 1- Bucquoy S. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut NATIONALLICENCE 700 1- Pineau C. Groupe d'étude de la reproduction chez le mâle, INSERM CJF 91-04, Campus de Beaulieu, Avenue du Général Leclerc, F-35042, Rennes Cedex, (France) aut NATIONALLICENCE 700 1- Jégou B. Groupe d'étude de la reproduction chez le mâle, INSERM CJF 91-04, Campus de Beaulieu, Avenue du Général Leclerc, F-35042, Rennes Cedex, (France) aut NATIONALLICENCE 700 1- Jollès P. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut NATIONALLICENCE 700 1- Schoentgen F. Laboratoire des protéines, CNRS URA 1188, Université Ren'e Descartes, Paris 5, 45 rue des Saints-Pères, F-75270, Paris Cedex 06 aut NATIONALLICENCE 773 0- Experientia Birkhäuser-Verlag 52/2(1996-02-01), 101-110 0014-4754 52:2<101 1996 52 18 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer