caa a22 4500 47708463X CHVBK 20180405111500.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/BF00435964 doi (NATIONALLICENCE)springer-10.1007/BF00435964 A modular questionnaire for the assessment of longterm quality of life in leukaemia patients: The MRC/EORTC QLQ-LEU [Elektronische Daten] [M. Watson, R. Zittoun, E. Hall, G. Solbu, K. Wheatley] We describe the psychometric analysis of a supplementary quality of life measure (MRC/EORTC QLQ-LEU) for evaluating long term sequelae of leukaemia treatments. The questionnaire under development was administered to 388 patients entered into the EORTC-GIMEMA AML 8A and the MRC AML10 clinical trials who were in complete remission for at least one year after completion of treatment on these trials. Results indicated a measure which is useful in evaluating the long-term effects of treatment in relation to chronic graft-vs-host disease and infection susceptibility. The performance of this measure in terms of its sensitivity and specificity between treatment arms was established by comparisons between the three treatment modalities in the above-mentioned trials and is the subject of further investigation. The new Leukaemia Module can be recommended for use alongside generic QOL instruments as a measure of long-term quality of life in leukaemia trials. Rapid Science Publishers, 1996 Watson M. The Royal Marsden NHS Trust, UK aut Zittoun R. Department of Haematology, Hotel Dieu, Paris, France aut Hall E. Clinical Trial Service Unit, Oxford, UK aut Solbu G. EORTC Data Centre, Brussels, Belgium aut Wheatley K. Clinical Trial Service Unit, Oxford, UK aut Quality of Life Research Kluwer Academic Publishers 5/1(1996-02-01), 15-19 0962-9343 5:1<15 1996 5 11136 https://doi.org/10.1007/BF00435964 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00435964 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Watson M. The Royal Marsden NHS Trust, UK aut NATIONALLICENCE 700 1- Zittoun R. Department of Haematology, Hotel Dieu, Paris, France aut NATIONALLICENCE 700 1- Hall E. Clinical Trial Service Unit, Oxford, UK aut NATIONALLICENCE 700 1- Solbu G. EORTC Data Centre, Brussels, Belgium aut NATIONALLICENCE 700 1- Wheatley K. Clinical Trial Service Unit, Oxford, UK aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 5/1(1996-02-01), 15-19 0962-9343 5:1<15 1996 5 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer