caa a22 4500 47708480X CHVBK 20180405111500.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/BF00435968 doi (NATIONALLICENCE)springer-10.1007/BF00435968 Health-related quality of life of HIV-infected women: evidence for the reliability, validity and responsiveness of the Medical Outcomes Study Short-Form 20 [Elektronische Daten] [M. Smith, J. Feldman, P. Kelly, J. DeHovitz, K. Chirgwin, H. Minkoff] The purpose of this study was to assess the reliability, validity and responsiveness of a health-related quality of life (HRQOL) instrument, the Medical Outcomes Short-Form 20-ltem General Health Survey (MOS SF-20), in a sample of women with the human immunodeficiency virus (HIV). Longitudinal data were collected on 202 HIV-infected women without AIDS who were receiving care at Kings County Hospital or SUNY Health Sciences Center, Brooklyn, New York. Internal consistency results showed acceptable reliability for the four multi-item MOS scales (role function, physical function, general health perceptions and mental health). Symptomatic patients and patients with lower Karnofsky Performance Status (KPS) ratings reported lower HRQOL than those who were asymptomatic or who had higher KPS scores. Patients who were older, unemployed or who had a history of injection drug use (IDU) also reported lower HRQOL. than those who were younger, employed or who had no drug use history. Adjusted mean scores on the MOS role and physical functioning scales proved sensitive to differences in clinical status over time. The MOS SF-20 is a reliable and valid instrument of HRQOL for women with HIV infection. Its sensitivity to differences in clinical status over time suggest that it may be useful as an HRQOL indicator for HIV/AIDS clinical trials. Rapid Science Publishers, 1996 Health-related quality of life nationallicence HIV-infected women nationallicence MOS SF-20 nationallicence Smith M. Memorial Sloan-Kettering Cancer Centre, New York, New York, USA aut Feldman J. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut Kelly P. Rush University College of Nursing, Chicago, Illinois, USA aut DeHovitz J. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut Chirgwin K. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut Minkoff H. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut Quality of Life Research Kluwer Academic Publishers 5/1(1996-02-01), 47-55 0962-9343 5:1<47 1996 5 11136 https://doi.org/10.1007/BF00435968 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00435968 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Smith M. Memorial Sloan-Kettering Cancer Centre, New York, New York, USA aut NATIONALLICENCE 700 1- Feldman J. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut NATIONALLICENCE 700 1- Kelly P. Rush University College of Nursing, Chicago, Illinois, USA aut NATIONALLICENCE 700 1- DeHovitz J. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut NATIONALLICENCE 700 1- Chirgwin K. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut NATIONALLICENCE 700 1- Minkoff H. Department of Preventive Medicine and Community Health of the State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 5/1(1996-02-01), 47-55 0962-9343 5:1<47 1996 5 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer