caa a22 4500 477084842 CHVBK 20180405111500.0 cr unu---uuuuu 170330e19961201xx s 000 0 eng 10.1007/BF00439229 doi (NATIONALLICENCE)springer-10.1007/BF00439229 King M. Centre for Health Economics Research and Evaluation, Westmead Hospital, 2145, Westmead, New South Wales, Australia aut The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30 [Elektronische Daten] [M. King] While quality of life (QOL) assessment is becoming more common, interpreting the results remains problematic. This paper demonstrates an approach to developing clinically-based interpretations for QOL outcomes, using the QLQ-C30 as an example. The results from 14 published QLQ-C30 studies which group patients by performance status, weight loss, toxicity, extent or severity of disease are collated. Groups with lower clinical status generally have worse QOL. The largest differences are between performance status groups, and the smallest differences are between groups of patients with local disease and those with metastases. The physical and role scores have the largest ranges of means across patient groups, and show the largest differences between clinical groups, while the cognitive and emotional scores have the smallest ranges of means and differences. Sicker groups have larger score standard deviations than healthie groups. Relatively large and small means and differences, and corresponding effect sizes, are presented. Collectively, the results provide a sense of the relative sizes of means and of differences, and of the types of clinical groups which give rise to them, thereby providing clinically-based benchmarks by which to interpret QLQ-C30 results. Rapid Science Publishers, 1996 Cancer nationallicence clinical importance nationallicence effect size nationallicence interpretations nationallicence quality of life nationallicence statistical significance nationallicence Quality of Life Research Kluwer Academic Publishers 5/6(1996-12-01), 555-567 0962-9343 5:6<555 1996 5 11136 https://doi.org/10.1007/BF00439229 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00439229 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- King M. Centre for Health Economics Research and Evaluation, Westmead Hospital, 2145, Westmead, New South Wales, Australia aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 5/6(1996-12-01), 555-567 0962-9343 5:6<555 1996 5 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer