caa a22 4500 477084885 CHVBK 20180405111501.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF00433924 doi (NATIONALLICENCE)springer-10.1007/BF00433924 Determinants of health-related quality of life after temporal lobe epilepsy surgery [Elektronische Daten] [K. Rose, P. Derry, S. Wiebe, R. McLachlan] Ternporal lobectomy appears to be an effective treatment for medically intractable epilepsy. However, the influences of pre-operative health status and post-operative reductions in seizure activity on post-surgical health-related quality of life (HRQOL) are not well understood. We used the Epilepsy Surgery Inventory 55 (ESI-55) to evaluate changes between pre- and post-operative HRQOL in 47 temporal lobectomy patients. Patients exhibited significantly improved scores in five HRQOL domains: health perceptions; energy fatigue; social function; cognitive function and role limitations due to physical problems. Although significant improvements in HRQOL were observed, this was not the case for all patients. Specifically, patients with low or medium pre-operative HRQOL scores were found to have the greatest degree of improvement post-operatively. Patients with high pre-operative scores did not exhibit these same improvements, although they continued to report high scores. The results indicate that the ESI-55 is a satisfactory instrument to measure change in HRQOL but also emphasizes that the magnitude of change in post-operative HRQOL scores tends to vary according to baseline scores. The outcome of temporal lobectomy is not entirely based upon the procedure's ability to reduce the frequency of seizures, but is also influenced by level of HRQOL prior to surgery. Rapid Science Publishers, 1996 Health-related quality of life nationallicence post-operative outcomes nationallicence seizures nationallicence temporal lobectomy nationallicence Rose K. Department of Psychology, University Hospital, London, Ontario, Canada aut Derry P. Department of Psychology, University Hospital, London, Ontario, Canada aut Wiebe S. Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada aut McLachlan R. Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada aut Quality of Life Research Kluwer Academic Publishers 5/3(1996-06-01), 395-402 0962-9343 5:3<395 1996 5 11136 https://doi.org/10.1007/BF00433924 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00433924 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rose K. Department of Psychology, University Hospital, London, Ontario, Canada aut NATIONALLICENCE 700 1- Derry P. Department of Psychology, University Hospital, London, Ontario, Canada aut NATIONALLICENCE 700 1- Wiebe S. Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada aut NATIONALLICENCE 700 1- McLachlan R. Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 5/3(1996-06-01), 395-402 0962-9343 5:3<395 1996 5 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer