caa a22 4500 47708494X CHVBK 20180405111501.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF00433918 doi (NATIONALLICENCE)springer-10.1007/BF00433918 A study of the reliability, validity and responsiveness of the HIV Overview of Problems Evaluation System (HOPES) in assessing the quality of life of patients with AIDS and symptomatic HIV infection [Elektronische Daten] [J. De Boer, M. Sprangers, N. Aaronson, J. Lange, F. van Dam] The objective of this study was to evaluate the feasibility, reliability, validity and responsiveness of the HIV Overview of Problems Evaluation System (HOPES) in a Dutch sample. The HOPES was administered three times in a one-year period to a sample of 106 outpatients with a symptomatic HIV-infection (n=23) or AIDS (n=83). The HOPES is a self-report HIV-specific quality of life (QOL) questionnaire including five scales: physical, psychosocial and sexual functioning, medical interaction and partner relationship. QOL was also assessed with the EORTC Quality of Life Questionnaire (EORTC QLQ-C30), a 30-item self-report instrument. Clinical data included Centers for Disease Control and Prevention (CDC) stage, date of diagnosis and CD4 cell count. Patients needed approximately 20-30 minutes to complete the questionnaire. The five scales had good internal consistency reliability. Multitrait scaling analysis provided moderate support for item discriminant and convergent validity. The HOPES exhibited adequate levels of construct validity: (1) the inter-scale correlations and correlations with the EORTC QLQ-C30 were in the predicted direction; (2) it discriminated clearly between patients with AIDS and ARC and (3) it was able to document changes in QOL over time. Moreover, the HOPES was responsive to changes in clinical status over time as indicated by CD4 counts. This study provides further evidence of the reliability and validity of the HOPES and shows that this instrument is responsive to changes in CD4 cell counts. Rapid Science Publishers, 1996 AIDS nationallicence HIV infections nationallicence HOPES nationallicence quality of life nationallicence reliability nationallicence validity nationallicence De Boer J. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut Sprangers M. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut Aaronson N. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut Lange J. Academic Medical Center, National AIDS Treatment Evaluation Center (NATEC), Amsterdam, The Netherlands aut van Dam F. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut Quality of Life Research Kluwer Academic Publishers 5/3(1996-06-01), 339-347 0962-9343 5:3<339 1996 5 11136 https://doi.org/10.1007/BF00433918 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00433918 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- De Boer J. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Sprangers M. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Aaronson N. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Lange J. Academic Medical Center, National AIDS Treatment Evaluation Center (NATEC), Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- van Dam F. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 5/3(1996-06-01), 339-347 0962-9343 5:3<339 1996 5 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer