caa a22 4500 477085253 CHVBK 20180405111502.0 cr unu---uuuuu 170330e19960401xx s 000 0 eng 10.1007/BF00434749 doi (NATIONALLICENCE)springer-10.1007/BF00434749 The impact of human immunodeficiency virus (HIV) infection on quality of life in a multiracial South African population [Elektronische Daten] [E. O'Keefe, R. Wood] We set out to document quality of life in South African HIV subjects, using the Medical Outcomes Survey (MOS) SF-36 instrument, and to determine whether this was affected by race, gender or clinical stage of disease. A cross-sectional survey of 134 HIV outpatients (42 White, 49 Mixed race, 43 Black) and 114 healthy non-medical hospital personnel (36 White, 37 Mixed race, 42 Black) was carried out at a referral centre for HIV patients in the Western Cape region of South Africa. Scores on eight scales measuring different aspects of quality of life were calculated. Black female controls scored significantly lower on all scales (p<0.05) except physical function. HIV-infected subjects of Mixed race (both genders) reported poorer physical function (p<0.05) but no other scale was affected by race. HIV subjects scored significantly lower than controls on all scales (p<0.01); the majority of the decline in function occurred early in disease by WHO stages 1 and 2. We conclude that HIV-infection impacts early on all aspects of quality of life and that this impact is largely independent of racial origin. Rapid Science Publishers, 1996 Human immunodeficiency virus (HIV) nationallicence Medical Outcomes Survey (MOS) Instrument SF-36 nationallicence race nationallicence quality of life nationallicence WHO Clinical disease stage nationallicence O'Keefe E. Department of Medicine, Somerset Hospital, University of Cape Town, South Africa aut Wood R. Department of Medicine, Somerset Hospital, University of Cape Town, South Africa aut Quality of Life Research Kluwer Academic Publishers 5/2(1996-04-01), 275-280 0962-9343 5:2<275 1996 5 11136 https://doi.org/10.1007/BF00434749 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00434749 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- O'Keefe E. Department of Medicine, Somerset Hospital, University of Cape Town, South Africa aut NATIONALLICENCE 700 1- Wood R. Department of Medicine, Somerset Hospital, University of Cape Town, South Africa aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 5/2(1996-04-01), 275-280 0962-9343 5:2<275 1996 5 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer