caa a22 4500 477086535 CHVBK 20180405111504.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/BF00171139 doi (NATIONALLICENCE)springer-10.1007/BF00171139 The nasopharyngeal bacterial flora in children with otitis media with effusion [Elektronische Daten] [I. Fujimori, K. Hisamatsu, K. Kikushima, R. Goto, Y. Murakami, T. Yamada] A study was undertaken to evaluate the incidence of nasopharyngeal α-streptococci with inhibitory activity against pathogens, as a defense mechanism of the normal bacterial flora against infection. Cultures were taken from the nasopharynges of 43 children with otitis media with effusion (OME). The detection rates of α-streptococci with inhibitory activity against Haemophilus influenzae, Streptococcus pneumoniae, Staphylococus aureus and group A streptococci were significantly lower in the nasopharynx than those isolated from the tonsils of the same patients. Moreover, the detection rates of α-streptococci with inhibitory activity against all of these pathogens derived from the nasopharynx were lower than those in healthy children, streptococcal strains with activity against H. influenzae and Strep. pneumoniae were also lower than that in patients with tonsillitis. These findings suggest that low nasopharyngeal levels of α-streptococci with inhibitory activity against respiratory pathogens may render children susceptible to OME. Further studies are needed to investigate the relationships between the prevalence of pathogens in the nasopharynx and the inhibitory activities of α-streptococci against them in order to devise and select optimal treatment for patients with OME. Springer-Verlag, 1996 Otitis media with effusion nationallicence Nasopharyngeal bacterial interference nationallicence α-Streptococcus nationallicence Children nationallicence Fujimori I. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut Hisamatsu K. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut Kikushima K. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut Goto R. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut Murakami Y. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut Yamada T. Department of Microbiology, Kajikazawa General Hospital, Yamanashi, Japan aut European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/4-5(1996-05-01), 260-263 0937-4477 253:4-5<260 1996 253 405 https://doi.org/10.1007/BF00171139 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00171139 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fujimori I. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut NATIONALLICENCE 700 1- Hisamatsu K. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut NATIONALLICENCE 700 1- Kikushima K. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut NATIONALLICENCE 700 1- Goto R. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut NATIONALLICENCE 700 1- Murakami Y. Department of Otolaryngology, Yamanashi Medical University, 1110 Shimo-kato, 409-38, Tamaho-cho, Yamanashi, Japan aut NATIONALLICENCE 700 1- Yamada T. Department of Microbiology, Kajikazawa General Hospital, Yamanashi, Japan aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/4-5(1996-05-01), 260-263 0937-4477 253:4-5<260 1996 253 405 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 477086535 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer