caa a22 4500 477086896 CHVBK 20180405111505.0 cr unu---uuuuu 170330e19960801xx s 000 0 eng 10.1007/BF00178290 doi (NATIONALLICENCE)springer-10.1007/BF00178290 Effects of pentoxifylline and nitroprusside on guinea pig cochlear blood flow in relationship to various hematocrit values [Elektronische Daten] [Y. Ohinata, K. Makimoto, H. Takahashi] To understand better the microcirculation in the inner ear in relation to blood viscosity, we examined the effects of pentoxifylline (PXF) and nitroprusside (NP) on cochlear blood flow (CBF) in healthy adult guinea pigs in relationship to various hematocrit (Ht) values. There was no correlation between Ht value and the maximum decrease of mean blood pressure after PXF infusion, whereas there was a positive correlation between Ht and the maximum increase in CBE No such relationship was found after NP infusion. A graph plot of each animal's blood oxygen transport capacity (i.e., Ht/blood viscosity) was found to have a convex form and to increase with a shift of the peak to a higher Ht area after PXF infusion. These findings indicate that a decrease in blood viscosity may improve CBF and increase oxygen transport capacity of blood. Springer-Verlag, 1996 Cochlear blood flow nationallicence Blood viscosity nationallicence Oxygen transport capacity nationallicence Pentoxifylline nationallicence Nitroprusside nationallicence Ohinata Y. Department of Otolaryngology, Saiseikai Nakatsu Hospital, 2-10-39, Shibata Kita-Ward, 530, Osaka, Japan aut Makimoto K. Department of Otolaryngology, Osaka Medical College, 2-7 Daigakucho Takatsuki, 569, Osaka, Japan aut Takahashi H. Department of Otolaryngology, Osaka Medical College, 2-7 Daigakucho Takatsuki, 569, Osaka, Japan aut European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/6(1996-08-01), 345-350 0937-4477 253:6<345 1996 253 405 https://doi.org/10.1007/BF00178290 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00178290 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ohinata Y. Department of Otolaryngology, Saiseikai Nakatsu Hospital, 2-10-39, Shibata Kita-Ward, 530, Osaka, Japan aut NATIONALLICENCE 700 1- Makimoto K. Department of Otolaryngology, Osaka Medical College, 2-7 Daigakucho Takatsuki, 569, Osaka, Japan aut NATIONALLICENCE 700 1- Takahashi H. Department of Otolaryngology, Osaka Medical College, 2-7 Daigakucho Takatsuki, 569, Osaka, Japan aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/6(1996-08-01), 345-350 0937-4477 253:6<345 1996 253 405 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer