caa a22 4500 477087108 CHVBK 20180405111506.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/BF00615121 doi (NATIONALLICENCE)springer-10.1007/BF00615121 Preliminary results of photodynamic therapy for recurrent nasopharyngeal carcinoma [Elektronische Daten] [M. Tong, C. van Hasselt, J. Woo] Photodynamic therapy (PDT) is a promising new modality in the treatment of cancer. In Hong Kong where nasopharyngeal carcinoma (NPC) is endemic, radiotherapy has been the primary treatment of choice. For recurrent disease after radiotherapy, there is no effective treatment. This latter report summarizes our initial experience in using PDT for these patients. Twelve patients (three females and nine males) with ages ranging from 33 to 65 years were treated with an infusion of hematoporphyrin derivative (5 mg/kg) 48-72 h before exposure to 200 J/cm2 light (wavelength, 630 nm) delivered from a gold vapor laser. All 12 patients showed a dramatic response as judged by computed tomography or magnetic resonance imaging at 6 months post-PDT. Of the eight patients in whom cure was aimed for, three remained disease-free at 9-12 months after a single treatment. Three of the remaining four patients achieved useful palliation. Skin hypersensitivity occurred in two patients and was the only significant complication encountered. This experience indicates that PDT can be an encouraging palliative or definitive management for recurrent superficial NPC. Springer-Verlag, 1996 Nasopharyngeal carcinoma nationallicence Photodynamic therapy nationallicence Management nationallicence Post-irradiation tumor recurrence nationallicence Tong M. Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong aut van Hasselt C. Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong aut Woo J. Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong aut European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/3(1996-01-01), 189-192 0937-4477 253:3<189 1996 253 405 https://doi.org/10.1007/BF00615121 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00615121 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tong M. Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong aut NATIONALLICENCE 700 1- van Hasselt C. Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong aut NATIONALLICENCE 700 1- Woo J. Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/3(1996-01-01), 189-192 0937-4477 253:3<189 1996 253 405 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer