caa a22 4500 477087280 CHVBK 20180405111507.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/BF00176696 doi (NATIONALLICENCE)springer-10.1007/BF00176696 Experimental topographic study of high-resolution tympanocochlear scintigraphy using the human temporal bone model [Elektronische Daten] [U. Ross, M. Reinhardt, P. Reuland] To determine the diagnostic value of tympanocochlear scintigraphy (TCS), which is still used for the visualization of alterations of labyrinthine bone metabolism due to active otosclerosis, resolution and detection limits were examined in a normal human temporal bone model. After incubation in technetium-99m-labeled diphosphonate solution, scintigraphic imaging showed the zygomatic process and the clivus as landmarks for fine structures of the petrous bone. For further differentiation, labyrinthine fine structures were marked with radioactive tracers of 0.5-1 mm2 each. High-resolution scintigraphic imaging gave two-point discrimination for structures as small as 2.5 mm apart. Localization of the activity patterns was improved by correlating imaging with X-ray photographs or by superimposition with masks of the prepared temporal bones drawn from the X-rays. The correlation of scintigraphic findings with X-ray photographs was found to provide a powerful method for improving the accuracy of localizing temporal bone metabolic changes as it is applicable clinically for studying the occurrence of small active otosclerotic foci. Springer-Verlag, 1996 Temporal bone nationallicence Labyrinth nationallicence Bone metabolism nationallicence Otosclerosis nationallicence Radionuclide imaging nationallicence Ross U. Department of Oto-Rhino-Laryngology, University of Freiburg, Killianstrasse 5, D-79106, Freiburg, Germany aut Reinhardt M. Department of Nuclear Medicine, University of Freiburg, Hugstetter Strasse 55, D-79106, Freiburg, Germany aut Reuland P. Practice for Nuclear Medicine, Schwabentorplatz 6, D-78098, Freiburg, Germany aut European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/1-2(1996-01-01), 17-20 0937-4477 253:1-2<17 1996 253 405 https://doi.org/10.1007/BF00176696 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00176696 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ross U. Department of Oto-Rhino-Laryngology, University of Freiburg, Killianstrasse 5, D-79106, Freiburg, Germany aut NATIONALLICENCE 700 1- Reinhardt M. Department of Nuclear Medicine, University of Freiburg, Hugstetter Strasse 55, D-79106, Freiburg, Germany aut NATIONALLICENCE 700 1- Reuland P. Practice for Nuclear Medicine, Schwabentorplatz 6, D-78098, Freiburg, Germany aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/1-2(1996-01-01), 17-20 0937-4477 253:1-2<17 1996 253 405 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer