caa a22 4500 477087302 CHVBK 20180405111507.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/BF00176703 doi (NATIONALLICENCE)springer-10.1007/BF00176703 A comparative study on the effect of pure-tone exposure of the guinea pig cochlea [Elektronische Daten] [S. Hotta, T. Sugisawa, T. Rob, M. Hasebe, K. Yamamura] Electrophysiological methods were applied to 160 healthy adult male guinea pigs in order to investigate the effects of pure-tone exposure for 24 h on the inner ear. A reduction in cochlear microphonics (CM), action potential (AP) and endocochlear potential was observed following exposure to 110 dB at 100 Hz, 100 dB at 200 and 600 Hz and 95 dB at 2 kHz. The observed K+ endolymphatic concentration during 40 min anoxia remained unchanged. In contrast K+ decreased in control animals and following exposure to pure tones varying from 110 dB at 60 Hz to 85 dB at 2 kHz. These findings indicate that high frequency tones have a greater effect on inner ear functions than those of lower frequency, decreasing the maximum output voltage of CM and AP but not changing K+ endolymphatic concentration. Springer-Verlag, 1996 Noise exposure nationallicence Pure-tone hearing losses nationallicence Guinea pig cochlea nationallicence Cochlear microphonics nationallicence Endolymph potassium nationallicence Hotta S. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut Sugisawa T. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut Rob T. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut Hasebe M. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut Yamamura K. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/1-2(1996-01-01), 45-51 0937-4477 253:1-2<45 1996 253 405 https://doi.org/10.1007/BF00176703 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00176703 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hotta S. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut NATIONALLICENCE 700 1- Sugisawa T. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut NATIONALLICENCE 700 1- Rob T. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut NATIONALLICENCE 700 1- Hasebe M. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut NATIONALLICENCE 700 1- Yamamura K. Department of Hygiene, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Japan aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/1-2(1996-01-01), 45-51 0937-4477 253:1-2<45 1996 253 405 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer