caa a22 4500 477087434 CHVBK 20180405111507.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/BF00179956 doi (NATIONALLICENCE)springer-10.1007/BF00179956 Expression of epidermal growth factor, epidermal growth factor receptor and transforming growth factor-alpha in the human fetal inner ear [Elektronische Daten] [H. Yamashita, M. Takahashi, D. Bagger-Sjöbäck] The expression of epidermal growth factor (EGF), EGF receptor and transforming growth factor (TGF)-alpha was analyzed in the human fetal inner ear using immuno-histochemical methods. EGF receptor was observed only in 9.5-week-old fetal vestibular epithelia. In 14- and 16-week-old fetuses, EGF receptor could not be detected. TGF-alpha was observed strongly in the 9- and 11-week-old vestibular epithelia, whereas only trace amounts were detectable in the 14- and 16-week-old vestibular epithelia. These findings suggest that EGF and TGF-alpha probably have a mitogenic effect in the sensory epithelia of the fetal inner ear, especially at early stages of development. Springer-Verlag, 1996 Epidermal growth factor nationallicence Epidermal growth factor receptor nationallicence Transforming growth factor-alpha Human fetal inner ear nationallicence Development nationallicence Yamashita H. Department of Otolaryngology, Yamaguchi University School of Medicine, 755, Ube, Yamaguchi, Japan aut Takahashi M. Department of Otolaryngology, Yamaguchi University School of Medicine, 755, Ube, Yamaguchi, Japan aut Bagger-Sjöbäck D. Department of Otolaryngology, Karolinska Hospital Karolinska Institute, Stockholm, Sweden aut European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/8(1996-11-01), 494-497 0937-4477 253:8<494 1996 253 405 https://doi.org/10.1007/BF00179956 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00179956 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yamashita H. Department of Otolaryngology, Yamaguchi University School of Medicine, 755, Ube, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Takahashi M. Department of Otolaryngology, Yamaguchi University School of Medicine, 755, Ube, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Bagger-Sjöbäck D. Department of Otolaryngology, Karolinska Hospital Karolinska Institute, Stockholm, Sweden aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer-Verlag 253/8(1996-11-01), 494-497 0937-4477 253:8<494 1996 253 405 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer